. 2018 Mar 20;18:103. doi: 10.1186/s12906-018-2166-0

Table 1.

The effect of AGME on MDA level, % inhibition of O₂⁻, GPx activity, and MAO-A,B activities of cerebral cortex and striatum areas of mice after MPTP treatment

Groups	MDA (μmol/mg protein)		% inhibition of O2-		GPx activity (Unit/g protein)		MAO-A activity (μmol/min.g tissue)		MAO-B activity (μmol/min.g tissue)
Groups	cortex	striatum	cortex	striatum	cortex	striatum	cortex	striatum	cortex	striatum
Control	2.22 ± 0.26	1.53 ± 0.56	16.48 ± 2.14	19.87 ± 1.99	18.45 ± 1.70	20.87 ± 1.68	3.00 ± 1.01	2.73 ± 1.05	5.01 ± 1.01	4.73 ± 1.05
Vehicle+MPTP	6.34 ± 0.41^a	5.96 ± 0.22^a	5.16 ± 1.46^a	8.32 ± 1.10^a	5.09 ± 2.27^a	6.54 ± 2.04^a	9.02 ± 1.00^a	10.13 ± 1.18^a	15.00 ± 1.04^a	17.13 ± 1.18^a
Tidomet plus 25 + MPTP	2.81 ± 0.48^b	1.70 ± 0.13^b	13.08 ± 1.95^b	11.87 ± 2.03^b	15.92 ± 0.81^b	13.41 ± 1.61^b	5.46 ± 0.67^b	6.16 ± 1.25^a	10.46 ± 0.67^b	8.16 ± 1.25^b
AGME 125 + MPTP	2.93 ± 0.41	4.77 ± 0.15	10.85 ± 1.55	9.98 ± 2.55	6.19 ± 1.81	7.83 ± 0.93	8.51 ± 1.19	9.56 ± 1.34	11.51 ± 1.19	10.56 ± 1.34
AGME 250 + MPTP	2.12 ± 0.43^b	3.75 ± 0.12^b	12.05 ± 1.99^b	14.04 ± 2.26^b	10.55 ± 1.18^b	12.37 ± 1.15^b	5.86 ± 0.68^b	6.70 ± 0.57 ^b	10.86 ± 0.68^b	8.70 ± 0.57b
AGME 375 + MPTP	2.01 ± 0.35^b	0.17 ± 0.19 ^b	15.75 ± 1.13^b	18.14 ± 1.26^b,c	16.54 ± 1.16^b	18.71 ± 1.26^b,c	4.21 ± 0.52^b	3.42 ± 0.72^b,c	6.21 ± 0.53^b,c	4.42 ± 0.72^b,c

Data were represented as mean ± S.D. of three replicates, n = 8 each, a vs. control group, p < 0.01; b vs. vehicle+MPTP-treated group, p < 0.05; c vs.Tidomet plus 25 + MPTP-treated group, p < 0.05