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. 2018 Mar 20;16:59. doi: 10.1186/s12957-018-1352-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — c-Myc bound to FoxM1 gene promoter. a The schematic graph of relative positions of c-Myc binding sites in FoxM1 gene promoter. b PC-3 cells were transfected with c-Myc overexpression plasmid and small interference RNA. The binding of c-Myc on site 1 of FoxM1 promoter in c-Myc overexpression group and control group was detected by ChIP assay. c The binding of c-Myc on site 2 of FoxM1 promoter in c-Myc overexpression group and control group was detected by ChIP assay. d The binding of c-Myc on site 1 of FoxM1 promoter in c-Myc interference group and control group was detected by ChIP assay. e The binding of c-Myc on site 2 of FoxM1 promoter in c-Myc interference group and control group was detected by ChIP assay. (*p < 0.05, **p < 0.01)