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. 2018 Mar 20;18:302. doi: 10.1186/s12885-018-4212-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Radiographic results before and after ICP inhibitors. The CT scan shows the primary lesion in the right upper lobe before the first-line ICP inhibitor (a), SD after 2 months accompanied by alveolitis (c, d), and enlarged after 4 months (b). After the failure of five lines of chemotherapy (e), the primary lesion responded to 3 cycles of nivolumab (f)