Table 2.
Characteristics of women who initiated ART and stopped ART under PMTCTB+, and factors associated with all cause ART attrition
| Initiated ART, n (%) | All cause attrition, n (%) | cHR (95% CI) | p | aHR (95% CI) (n = 436) | p | |
|---|---|---|---|---|---|---|
| Total | 496 | 209 | ||||
| CD4 (n = 496) | ||||||
| 0–349 | 224 (45.2) | 80 (38.3) | Reference | Reference | ||
| 350–499 | 132 (26.6) | 57 (27.3) | 1.29 (0.92,1.82) | 0.144 | 1.21 (0.88,1.66) | 0.251 |
| ≥500 | 119 (24.0) | 62 (29.6) | 1.70 (1.22,2.37) | 0.002 | 1.28 (0.92,1.78) | 0.138 |
| Missing | 21 (4.2) | 10 (4.8) | 1.93 (1.00,3.73) | 0.050 | 2.06 (0.98,4.34) | 0.057 |
| WHO (n = 496) | ||||||
| I + II | 416 (83.9) | 176 (84.2) | Reference | Reference | ||
| III + IV | 11 (2.2) | 5 (2.4) | 1.24 (0.51,3.01) | 0.639 | ||
| Missing | 69 (13.9) | 28 (13.4) | 1.23 (0.82,1.84) | 0.317 | ||
| Age group (n = 495) | ||||||
| 16–24 | 197 (39.7) | 96 (45.9) | Reference | Reference | ||
| 25–34 | 260 (52.4) | 97 (46.4) | 0.70 (0.53,0.93) | 0.014 | 0.75 (0.57,0.99) | 0.046 |
| ≥35 | 38 (7.7) | 16 (7.7) | 0.86 (0.51,1.46) | 0.580 | 0.99 (0.61,1.61) | 0.979 |
| Missing | 1 (0.2) | 0 (0) | ___ | |||
| HIV diagnosis (n = 492) | ||||||
| New | 307 (61.9) | 126 (60.3) | Reference | |||
| Previously diagnosed | 185 (37.3) | 83 (39.7) | 1.11 (0.84,1.47) | 0.46 | ||
| Missing | 4 (0.8) | 0 (0) | ___ | |||
| Trimester (n = 450) | ||||||
| 1st | 50 (10.1) | 15 (7.2) | Reference | Reference | ||
| 2nd | 318 (64.1) | 129 (61.7) | 1.61 (0.93,2.80) | 0.089 | 1.49 (0.94,2.38) | 0.091 |
| 3rd | 82 (16.5) | 43 (20.6) | 2.56 (1.40.4.68) | 0.002 | 2.37 (1.39,4.01) | 0.001 |
| Missing | 46 (9.3) | 22 (10.5) | ___ | |||
| Pregnancy (n = 494) | ||||||
| 1st | 100 (21.2) | 44 (21) | Reference | |||
| ≥2nd | 394 (79.4) | 164 (78.5) | 0.87 (0.62,1.22) | 0.419 | ||
| Missing | 2 (0.4) | 1 (0.5) | ___ | |||
| Health care facility (n = 496) | ||||||
| Primary | 253 (51.0) | 90 (43.1) | Reference | Reference | ||
| Secondary | 243 (49.0) | 119 (56.9) | 1.46 (1.11,1.92) | 0.007 | 1.98 (1.50,2.60) | < 0.001 |
| ART initiation (n = 496) | ||||||
| Deferred | 380 (76.6) | 160 (76.6) | Reference | |||
| Same-day | 116 (23.4) | 49 (23.4) | 1.10 (0.80,1.52) | 0.451 | ||
| Enrolment phase (n = 496) | ||||||
| Early | 150 (30.2) | 63 (30.1) | Reference | |||
| Mid | 148 (29.8) | 65 (31.1) | 1.32 (0.93,1.88) | 0.124 | 1.48 (1.05,2.08) | 0.025 |
| Late | 198 (39.9) | 81 (38.8) | 1.50 (1.06,2.12) | 0.024 | 1.67 (1.18,2.37) | 0.004 |
cHR crude hazard ratio, aHR adjusted hazard ratio