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. 2018 Mar 16;14:557–564. doi: 10.2147/TCRM.S157469

Table 2.

Potentially inappropriate medications to be avoided regardless of diagnosis of geriatric patients (n=400) in pre-intervention and intervention groups based on 2015 Beers criteria

Organ system/therapeutic category/drug(s) Pre-intervention N=200
n (%)
Intervention N=200
n (%)
p-value*
First-generation antihistamines 32 (16.0) 9 (4.5) <0.001
Insulin, sliding scale 37 (18.5) 13 (6.5) <0.001
Antispasmodics 18 (9.0) 7 (3.5) 0.023
Alpha1 blockers 14 (7.0) 4 (2.0) 0.016
Alpha agonists 11 (5.5) 5 (2.05) 0.201
Antiarrhythmic drugs (class Ia, Ic, III) 30 (15.0) 12 (6.0) 0.003
Digoxin 11 (5.5) 9 (4.5) 0.646
Tertiary TCAs 13 (6.5) 4 (2.0) 0.026
Antipsychotics 13 (6.5) 7 (3.5) 0.169
Barbiturates 13 (6.5) 4 (2.0) 0.044
Benzodiazepines 19 (9.5) 6 (3.0) 0.007
Antiparkinson agents 7 (3.5) 3 (1.5) 0.338
Sulfonylureas, long-duration 31 (15.5) 14 (7.0) 0.007
Metoclopramide 29 (14.5) 11 (5.5) 0.003
Meperidine 11 (5.5) 8 (4.0) 0.638

Note:

*

Chi-square test.

Abbreviation: TCAs, tricyclic antidepressants.