Table 5.
Multivariate linear regression analysis of platelet SERT of different models and pretreatments
| Platelet SERT | Unstandardized coefficients
|
Standardized coefficients
|
t | Sig | |
|---|---|---|---|---|---|
| B | Std error | Beta | |||
| Constant | 274.03 | 8.64 | 31.724 | 0.000 | |
| x1 | 48.82 | 12.22 | 0.355 | 3.996 | 0.000 |
| x2 | 4.18 | 12.22 | 0.029 | 0.342 | 0.734 |
| x3 | 7.80 | 12.22 | 0.054 | 0.638 | 0.527 |
| x4 | −120.89 | 11.43 | −0.989 | −10.580 | 0.000 |
| x1*x4 | 45.93 | 16.16 | 0.272 | 2.842 | 0.007 |
| x2*x4 | 30.77 | 16.73 | 0.161 | 1.840 | 0.073 |
| x3*x4 | 8.80 | 16.73 | 0.046 | 0.526 | 0.602 |
Notes: Constant: sham pretreated with saline; y: value of platelet SERT; x1: MI pretreated with saline; x2: depression pretreated with saline; x3: MI + depression pretreated with saline; x4: pretreated with trimetazidine; x1*x4: the interaction of MI and trimetazidine; x2*x4: the interaction of depression and trimetazidine; x3*x4: the interaction of MI + depression and trimetazidine.
Abbreviations: MI, myocardial infarction; SERT, serotonin transporter.