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. Author manuscript; available in PMC: 2018 Mar 21.
Published in final edited form as: Bone Marrow Transplant. 2017 Sep 18;52(12):1616–1622. doi: 10.1038/bmt.2017.198

Table 4.

Cause of Death

Renal function at HCT
Normal/Mild Moderate Severe/RI
Number of patients 1240 185 67
Number of death 315 49 22
Cause of death
 Primary disease 255 (81) 36 (73) 16 (73)
 Infection 8 (3) 2 (4) 0
 Organ failure1 9 (3) 3 (6) 2 (9)
 Secondary malignancy 5 (2) 1 (2) 1 (5)
 Other2 8 (3) 2 (4) 0
 Unknown 30 (9) 5 (10) 3 (14)
1

Organ failure: Normal/Mild: ARDS (2), Cardiac (2), Renal (2), TTP/HUS (1), Not specified (2); Moderate: ARDS (2), Cardiac (1); Severe/RF: Pulmonary Edema (1), Renal (1)·

2

Intracranial (1), subarachnoid hemorrhage (1), accidental death (1), thromboembolic (1), prior malignancy (1), hypoxemia, sepsis, hypotension, neutropenia (1), perforated viscus (1), respiratory failure (1), septic shock (1), severe metabolic acidosis (1).

(severe metabolic acidosis: Moderate renal function at HCT)

3

HCT, hematopoietic cell transplantation; RI, renal insufficiency