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. 2018 Mar 13;9:435. doi: 10.3389/fimmu.2018.00435

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Copyright © 2018 Serve, Sturm, Schimunek, Störmann, Heftrig, Teuben, Oppermann, Horst, Pfeifer, Simon, Kalbas, Pape, Hildebrand, Marzi and Relja.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative counts of lymphocytes and CD4⁺ lymphocytes in human and porcine peripheral blood. (A) Gating strategy for lymphocytes before trauma. (B) Proportions of lymphocytes of all leukocytes before and after trauma. (C) Dot plot analysis of human and porcine peripheral blood obtained before trauma and stained with human and porcine CD4 antibody, respectively. (D) Relative count of CD4⁺ lymphocytes before and after trauma in percent. Means and SEM are shown. HV: healthy volunteers; AT: immediately after trauma; D1: 24 h after trauma; D3: 72 h after trauma; polytrauma patients: n = 20, HV: n = 10, animals: n = 10; *: significantly different (p < 0.05) to HV or ctrl, respectively.