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. 2018 Mar 13;9:435. doi: 10.3389/fimmu.2018.00435

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Copyright © 2018 Serve, Sturm, Schimunek, Störmann, Heftrig, Teuben, Oppermann, Horst, Pfeifer, Simon, Kalbas, Pape, Hildebrand, Marzi and Relja.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proportions of CD4⁺CD25⁺ lymphocytes in peripheral blood before and after trauma. (A–D) Gating strategies for human CD4⁺CD25⁺ lymphocytes. (E–H) Gating strategies for porcine CD4⁺CD25⁺ lymphocytes. (I) Relative counts of CD4⁺CD25⁺ lymphocytes compared according to different time-points in percent. Means and SEM are shown. HV: healthy volunteers; AT: immediately after trauma; D1: 24 h after trauma; D3: 72 h after trauma; polytrauma patients: n = 20, HV: n = 10, animals: n = 10; *: significantly different (p < 0.05) to HV or ctrl, respectively.