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. 2018 Feb 1;32(3-4):224–229. doi: 10.1101/gad.306464.117

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© 2018 Sansam et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 3. — BET proteins recruit TICRR to chromatin. (A) Representative nuclei of cells expressing EGFP-tagged TICRR or TICRR-8A. The square marks the area photobleached. Images were taken at the indicated times after photobleaching. (B) Relative fluorescence in the bleached region for replicate FRAP experiments in which images were taken every 10 sec. (C) Times to 50% fluorescence recovery for experiments shown in B. Fifty percent recovery times were calculated from fitted curves. Mean ± SD. (****) P < 0.0001. (D) Times to 50% recovery for FRAP of synchronized cells in early or late S phase. Mean ± SD. (**) P = 0.0042; (****) P < 0.0001.