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. 2017 May 23;186(8):952–960. doi: 10.1093/aje/kwx167

Table 1.

Spearman's Correlationa Between 1,5-Anhydroglucitol, Other Glycemic Markers, and Kidney Filtration Markers in the Overall Study Population, According to Diabetes Status and Categories of Estimated Glomerular Filtration Rateb, Atherosclerosis Risk in Communities Study, United States, 1990–1992

Marker Overall eGFRCr-Cys <60 eGFRCr-Cys 60–89 eGFRCr-Cys 90–134 eGFRCr-Cys ≥135
r P Value r P Value r P Value r P Value r P Value
Total Study Populationc
Fasting glucose −0.17 <0.001 −0.35 <0.001 −0.17 <0.001 −0.16 <0.001 −0.68 <0.001
HbA1c −0.25 <0.001 −0.53 <0.001 −0.25 <0.001 −0.24 <0.001 −0.66 <0.001
Fructosamine −0.28 <0.001 −0.47 <0.001 −0.27 <0.001 −0.27 <0.001 −0.70 <0.001
Glycated albumin −0.29 <0.001 −0.41 <0.001 −0.27 <0.001 −0.28 <0.001 −0.70 <0.001
eGFRCr-Cys −0.11 <0.001 0.25 <0.001 −0.001 0.5 −0.12 <0.001 −0.25 0.05
eGFRβ2M −0.11 <0.001 0.16 0.002 −0.06 <0.001 −0.12 <0.001 −0.15 0.2
Participants Without Diagnosed Diabetesd
Fasting glucose −0.02 0.03 −0.08 0.2 −0.03 0.06 −0.02 0.1 −0.28 0.06
HbA1c −0.09 <0.001 −0.14 0.02 −0.09 <0.001 −0.09 <0.001 −0.35 0.02
Fructosamine −0.13 <0.001 −0.11 0.07 −0.13 <0.001 −0.14 <0.001 −0.30 0.04
Glycated albumin −0.14 <0.001 −0.02 0.7 −0.12 <0.001 −0.15 <0.001 −0.29 0.05
eGFRCr-Cys −0.12 <0.001 0.13 0.03 −0.03 0.05 −0.11 <0.001 −0.21 0.2
eGFRβ2M −0.14 <0.001 −0.002 0.9 −0.10 <0.001 −0.13 <0.001 −0.24 0.1
Participants With Diagnosed Diabetese
Fasting glucose −0.77 <0.001 −0.60 <0.001 −0.76 <0.001 −0.79 <0.001 −0.28 0.3
HbA1c −0.84 <0.001 −0.76 <0.001 −0.83 <0.001 −0.86 <0.001 −0.58 0.01
Fructosamine −0.83 <0.001 −0.65 <0.001 −0.81 <0.001 −0.85 <0.001 −0.32 0.2
Glycated albumin −0.83 <0.001 −0.62 <0.001 −0.81 <0.001 −0.86 <0.001 −0.28 0.2
eGFRCr-Cys −0.19 <0.001 0.07 0.4 −0.02 0.8 −0.17 <0.001 −0.24 0.3
eGFRβ2M −0.17 <0.001 0.17 0.07 −0.002 0.9 −0.14 <0.001 −0.008 0.9

Abbreviations: eGFRβ2M, estimated glomerular filtration rate based on β2-microglobulin; eGFRCr-Cys, estimated glomerular filtration rate based on creatinine and cystatin C; HbA1c, glycated hemoglobin.

a Spearman's rank correlation coefficients and P values.

b eGFRCr-Cys in units of mL/min/1.73 m2; 87 participants were missing data for cystatin C.

c The overall number of subjects was 13,277; for the categories of eGFRCr-Cys <60, 60–89, 90–134, and ≥135, the numbers of participants were 370, 4,207, 8,547, and 66, respectively.

d The overall number of subjects without diagnosed diabetes was 12,033; for the categories of eGFRCr-Cys <60, 60–89, 90–134, and ≥135, the numbers of participants were 260, 3,828, 7,825, and 47, respectively.

e The overall number of subjects with diagnosed diabetes was 1,244; for the categories of eGFRCr-Cys <60, 60–89, 90–134, and ≥135, the numbers of participants were 110, 379, 722, and 19, respectively.