Table 3.
TIP cutoff | aMCI vs. controls | aMCI and dementia vs. controls | Dementia vs. controls and aMCI | |||
---|---|---|---|---|---|---|
Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | Specificity | |
≤13 | 0.16 (0.05,0.34) | 0.96 (0.93,0.98) | 0.37 (0.24,0.52) | 0.96 (0.93,0.98) | 0.70 (0.46,0.88) | 0.95 (0.92,0.97) |
≤14 | 0.26 (0.12,0.45) | 0.96 (0.93,0.98) | 0.45 (0.31,0.60) | 0.96 (0.93,0.98) | 0.75 (0.51,0.91) | 0.94 (0.90,0.96) |
≤15 | 0.35 (0.19,0.55) | 0.95 (0.91,0.97) | 0.53 (0.38,0.67) | 0.95 (0.91,0.97) | 0.80 (0.56,0.94) | 0.91 (0.87,0.94) |
≤16 | 0.39 (0.22,0.58) | 0.93 (0.89,0.96) | 0.59 (0.44,0.72) | 0.93 (0.89,0.96) | 0.90 (0.68,0.99) | 0.89 (0.85,0.93) |
≤17c | 0.48 (0.30,0.67) | 0.91 (0.87,0.95) | 0.67 (0.52,0.79) | 0.91 (0.87,0.95) | 0.95 (0.75,1.00) | 0.87 (0.82,0.91) |
≤18 | 0.52 (0.33,0.70) | 0.88 (0.83,0.92) | 0.69 (0.54,0.81) | 0.88 (0.83,0.92) | .95 (0.75,1.00) | 0.83 (0.78,0.88) |
≤19 | 0.58 (0.39,0.75) | 0.83 (0.78,0.88) | 0.75 (0.60,0.86) | 0.83 (0.78,0.88) | 1.00 (0.83,1.00) | 0.79 (0.73,0.83) |
≤20 | 0.61 (0.42,0.78) | 0.80 (0.74,.85) | 0.76 (0.63,0.87) | 0.80 (0.74,0.85) | 1.00 (0.83,1.00) | 0.75 (0.70,0.80) |
≤21 | 0.68 (0.49,0.83) | 0.77 (0.71,0.82) | 0.80 (0.67,0.90) | 0.77 (0.71,0.82) | 1.00 (0.83,1.00) | 0.72 (0.66,0.77) |
≤22d | 0.74 (0.55,0.88) | 0.73 (0.67,0.79) | 0.84 (0.71,0.93) | 0.73 (0.67,0.79) | 1.00 (.83,1.00) | 0.68 (0.62,0.73) |
≤23 | 0.77 (0.59,0.90) | 0.66 (0.60,0.72) | 0.86 (0.74,0.94) | 0.66 (0.60,0.72) | 1.00 (0.83,1.00) | 0.61 (0.55,0.67) |
≤24 | 0.81 (0.63,0.93) | 0.62 (0.55,0.68) | 0.88 (0.76,0.96) | 0.62 (0.55,0.68) | 1.00 (0.83,1.00) | 0.57 (0.51,0.63) |
≤25 | 0.84 (0.66,0.95) | 0.52 (0.46,0.59) | 0.90 (0.79,0.97) | 0.52 (0.46,0.59) | 1.00 (0.83,1.00) | 0.48 (0.42,0.54) |
≤26 | 0.87 (0.70,0.96) | 0.45 (0.38,0.51) | 0.92 (0.81,0.98) | 0.45 (0.38,0.51) | 1.00 (0.83,1.00) | 0.41 (0.35,0.47) |
≤27 | 0.94 (0.79,0.99) | 0.37 (0.31,0.43) | 0.96 (0.87,1.00) | 0.37 (0.31,0.43) | 1.00 (0.83,1.00) | 0.34 (0.28,0.39) |
≤28 | 0.97 (0.83,1.00) | 0.29 (0.24,0.35) | 0.98 (0.90,1.00) | 0.29 (0.24,0.35) | 1.00 (0.83,1.00) | 0.26 (0.21,0.32) |
Notes: MBT, Memory Binding Test; TIP, The Total number of Items cued recalled in the Paired condition on the MBT; aMCI, amnestic mild cognitive impairment.
aResults excluded persons with naMCI. Supplementary Table S6 shows the corresponding results that included persons with naMCI.
bThe optimal cut-scores were chosen to maximize the sum of sensitivity and specificity.
cThe optimal cut-score for distinguishing dementia from controls and aMCI.
dThe optimal cut-score for distinguishing aMCI or aMCI and dementia from controls.