Figure 1.

Estimated prevalence of masked hypertension in the United States, by age, 2005–2010. Estimates were based on multiple imputation (500 data sets) of hypertension status as defined by ambulatory blood pressure for 9,316 adult participants in the National Health and Nutrition Examination Survey (2005–2010) with nonelevated clinic blood pressure, no history of overt cardiovascular disease, and no use of antihypertensive medication. A locally weight scatterplot smoothing (LOESS) curve using second-degree polynomials (black line) was fitted to the 65 age-specific estimates (black circles), with weights proportional to the inverse of each estimate's squared standard error; the smoothing parameter (1.00) was selected to optimize the generalized cross-validation criterion (36). Gray area, 95% confidence interval.