Table 3.
Patient characteristics of Austrian patients with stable CAD and Austrian patients with stable CAD and angina during observationi
| Parameter | 1st year | 2nd year | 3rd year | 4th year | 5th year |
|---|---|---|---|---|---|
| Patients with stable CAD (N [%]) | |||||
| N | 411 | 351 | 337 | 323 | 305 |
| Weight [kg] | 81.6 (13.8) | 81.9 (13.5) | 82.1 (14.7) | 81.9 (13.5) | 81.4 (14.0) |
| BMI, mean (SD) [kg/m2] | 27.7 (4.0) | 27.9 (4.0) | 27.9 (4.3) | 27.7 (3.9) | 27.6 (3.9) |
| HR (palpation), mean (SD) [bpm] | 66.7 (9.6) | 66.2 (9.9) | 66.4 (11.3) | 66.4 (10.3) | 67.3 (11.3) |
| HR (ECG), mean (SD) [bpm] | 66.0 (10.0) | 65.8 (9.8) | 66.1 (11.5) | 66.5 (11.3) | 67.0 (11.0) |
| SBP, mean (SD), [mm Hg] | 133.4 (17.4) | 132.9 (18.8) | 133.3 (17.1) | 134.3 (17.9) | 133.7 (16.8) |
| DBP mean (SD), [mm Hg] | 79.3 (9.3) | 78.5 (9.5) | 78.8 (9.4) | 78.9 (9.7) | 78.4 (9.4) |
| Waist circumference, mean (SD), [cm] | 99.3 (12.0) | 98.6 (11.5) | 99.7 (13.1) | 99.4 (11.2) | 100.1 (13.6) |
| Overweight (%)a | 305 (76.2) | 270 (78.3) | 253 (76.0) | 232 (75.6) | 224 (75.7) |
| Obesity (%)b | 98 (24.5) | 85 (24.6) | 78 (23.4) | 74 (24.1) | 67 (22.6) |
| Smoking status (%) | |||||
| Current | 45 (11.0) | 35 (10.1) | 33 (9.9) | 29 (9.1) | 27 (9.1) |
| Former | 189 (46.3) | 157 (45.2) | 153 (45.7) | 135 (42.5) | 114 (38.3) |
| Never | 174 (42.6) | 155 (44.7) | 149 (44.5) | 154 (48.4) | 157 (52.7) |
| Raised blood pressure (%)c | 163 (40.8) | 125 (36.2) | 120 (36.0) | 129 (42.0) | 117 (39.5) |
| Raised LDL cholesterol 1 (%)d | 120 (36.4) | 96 (34.9) | 86 (34.1) | 72 (30.0) | 69 (30.5) |
| Raised LDL cholesterol 2 (%)e | 274 (83.0) | 225 (81.8) | 206 (81.7) | 193 (80.4) | 173 (76.5) |
| Lowered HDL cholesterol (%)f | 58 (16.6) | 48 (16.8) | 52 (19.3) | 53 (21.2) | 55 (23.3) |
| Raised HbA1c (%)g | 33 (28.0) | 22 (23.2) | 32 (35.6) | 30 (36.1) | 24 (31.2) |
| Smoking initiation (%)h | 6 (1.7) | 4 (1.3) | 5 (1.7) | 4 (1.4) | 5 (1.9) |
| Patients with stable CAD and angina | |||||
| N (%) | 35 (8.6) | 25 (7.2) | 14 (4.2) | 16 (5.0) | 7 (2.3) |
| Weight [kg] | 79.5 (15.3) | 81.9 (13.0) | 79.7 (12.9) | 76.9 (12.1) | 71.7 (15.3) |
| BMI, mean (SD) [kg/m2] | 26.9 (4.1) | 27.1 (3.5) | 27.2 (3.0) | 27.6 (4.3) | 24.0 (4.4) |
| HR (palpation), mean (SD) [bpm] | 69.5 (11.4) | 65.3 (12.0) | 71.1 (16.9) | 63.8 (9.0) | 62.3 (4.8) |
| HR (ECG), mean (SD) [bpm] | 68.5 (10.2) | 65.1 (13.5) | 68.4 (16.3) | 63.9 (9.3) | 63.3 (6.4) |
| HR ≥ 70 bpm (palpation) | 17 (48.6) | 5 (20.0) | 6 (42.9) | 3 (18.8) | 1 (14.3) |
| SBP, mean (SD), [mm Hg] | 129.8 (16.2) | 131.8 (22.3) | 140.0 (20.2) | 136.8 (20.7) | 138.0 (19.1) |
| DBP mean (SD), [mm Hg] | 77.2 (10.3) | 78.7 (8.4) | 79.7 (13.5) | 72.8 (11.3) | 81.0 (14.8) |
| Waist circumference, mean (SD), [cm] | 97.9 (13.5) | 101.0 (11.7) | 99.6 (11.6) | 99.7 (15.1) | 94.7 (12.9) |
| Overweight (%)a | 24 (68.6) | 19 (79.2) | 11 (78.6) | 10 (66.7) | 3 (50.0) |
| Obesity (%)b | 9 (25.7) | 4 (16.7) | 2 (14.3) | 5 (33.3) | 1 (16.7) |
| Smoking status N (%) | |||||
| Current | 5 (14.3) | 2 (8.0) | 1 (7.1) | 2 (12.5) | 1 (14.3) |
| Former | 14 (40.0) | 13 (52.0) | 6 (42.9) | 5 (31.2) | 3 (42.9) |
| Never | 16 (45.7) | 10 (40.0) | 7 (50.0) | 9 (56.2) | 3 (42.9) |
| Raised blood pressure (%)c | 9 (25.7) | 8 (33.3) | 7 (50.0) | 8 (53.3) | 3 (50.0) |
| Raised LDL cholesterol 1 (%)d | 14 (50.0) | 6 (30.0) | 3 (25.0) | 3 (25.0) | 2 (50.0) |
| Raised LDL cholesterol 2 (%)e | 25 (89.3) | 16 (80.0) | 9 (75.0) | 8 (66.7) | 4 (100.0) |
| Lowered HDL cholesterol (%)f | 5 (16.1) | 5 (23.8) | 3 (25.0) | 4 (28.6) | 1 (25.0) |
| Raised HbA1c (%)g | 3 (30.0) | 2 (25.0) | 2 (66.7) | 0 (0.0) | 0 (0.0) |
| Started smoking (%)h | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (14.3) |
BMI Body mass index, bpm beats per minute, CAD coronary artery disease, DBP diastolic blood pressure, HbA1c glycated hemoglobin, HDL high-density lipoprotein, HR heart rate, LDL low-density lipoprotein, N number of patients, SBP systolic blood pressure, SD standard deviation
aDefined as BMI ≥ 25–29.99 kg/m2
bDefined as BMI ≥ 30 kg/m2
cDefined as systolic blood pressure ≥140 mm Hg and diastolic blood pressure ≥90 mm Hg
dDefined as LDL cholesterol plasma level ≥1 g/l or 2.6 mmol/l
eDefined as LDL cholesterol plasma level ≥0.7 g/l or 1.8 mmol/l
fDefined as HDL cholesterol plasma level ≤40 mg/dl or 1.0 mmol/l
gin diabetic patients, defined as HbA1c level ≥7.0%
hfor former/never smokers at baseline
imean values as well as percentages are of the data available