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. 2017 Jul 4;33(21):3482–3485. doi: 10.1093/bioinformatics/btx424

Fig. 1.

Fig. 1

TITINdb user interface overview. The HMERF and TMD associated nsSNV hotspots are shown. Users can pin disease-associated nsSNVs from the SNV table onto domain structure and visualize these against the distribution of population nsSNVs (Gnomad or 1000 genomes). Pre-computed in silico analyses are shown in the SNV table (more information can be accessed by scrolling horizontally and vertically)