Table 4.
Biochemical parameters at end of clamp in patients with T2DM and control participants without diabetes
| Euglycemia | Hypoglycemia | Euglycemia vs. hypoglycemia adjusted P value | |
|---|---|---|---|
| Potassium (mmol/L) | |||
| Control | 3.69 ± 0.14 | 3.48 ± 0.11 | 0.40 |
| T2DM | 3.72 ± 0.13 | 3.27 ± 0.09 | 0.02 |
| Epinephrine (nmol/L) | |||
| Control | 0.14 ± 0.02 | 3.83 ± 0.85 | 0.0002 |
| T2DM | 0.16 ± 0.05 | 3.05 ± 0.71 | 0.003 |
| Norepinephrine (nmol/L) | |||
| Control | 1.56 ± 0.12 | 2.69 ± 0.44 | 0.002 |
| T2DM | 1.27 ± 0.09 | 2.45 ± 0.23 | 0.009 |
Data are mean ± SE. P value comparison between euglycemia and hypoglycemia by two-way ANOVA with multiple comparisons between glycemic arms and between participant groups. No significant differences were found between control participants without diabetes and patients with T2DM under either glycemic condition.