. 2017 May 19;186(3):356–366. doi: 10.1093/aje/kwx064

Table 3.

Comparison of Laboratory Characteristics of African Americans According to Their Place of Birth, Hepatitis B Research Network Study, North America, 2011–2013

Characteristic	All Participants			USAA			East African FBAA			West African FBAA			Other FBAA			P Value^a
Characteristic	Sample Size	Frequency	%	Sample Size	Frequency	%	Sample Size	Frequency	%	Sample Size	Frequency	%	Sample Size	Frequency	%	P Value^a
ALT, U/L
Men^b	126	37 (26–63)		26	55 (34–97)		56	33 (23–41)		36	46 (31–70)		8	33 (24–69)		0.001
Women^b	102	21 (16–27)		30	21 (18–27)		48	19 (14–25)		18	27 (20–43)		6	24 (20–165)		0.008
ALT, ULN^c	228			56			104			54			14			0.005
≤1.00		94	41		21	38		52	50		15	28		6	43
1.03–2.00		88	39		20	36		43	41		21	39		4	29
≥2.03		46	20		15	27		9	9		18	33		4	29
HBV DNA (log₁₀ IU/mL)^b	234	3.0 (2.0–3.9)		56	3.4 (2.3–4.5)		110	2.8 (1.9–3.4)		54	3.2 (2.1–4.1)		14	3.3(2.0–4.0)		0.025
HBV DNA, IU/mL	234			56			110			54			14			0.034
<1,000		120	51		24	43		68	62		22	41		6	43
1,000–9,999		61	26		15	27		26	24		15	28		5	36
10,000–99,999		17	7		5	9		7	6		5	9		0	0
100,000–999,999		15	6		1	2		6	5		7	13		1	7
1,000,000–9,999,999		6	3		3	5		1	1		2	4		0	0
≥10,000,000		15	6		8	14		2	2		3	6		2	14
Positive for anti-HDV	166	11	7	50	3	6	60	3	5	45	5	11	11	0	0	0.470
Positive for anti-HCV	172	7	4	46	4	9	73	3	4	42	0	0	11	0	0	0.179

Abbreviations: ALT, alanine aminotransferase; anti-HCV, antibody to the hepatitis C virus; anti-HDV, antibody to the hepatitis D virus; FBAA, foreign-born African Americans; HBV, hepatitis B virus; ULN, upper limit of normal; USAA, US-born African Americans.

^a The P values reflect the difference between USAAs, East African FBAAs, West African FBAAs, and other FBAAs.

^b Continuous variables were summarized by median (interquartile range).

^c ULN was 30 U/L for men and 20 U/L for women.