Table 2.
Comparison of the results from ZIBR and LMM for four bacterial genera, where three covariates, including the baseline abundance, time and treatment, were included in each model
|
LMM
|
ZIBR
|
|||||
|---|---|---|---|---|---|---|
| Species | Baseline | Time | Treatment | Baseline | Time | Treatment |
| Lactobacillus | 1.10E-11 | 5.68E-02 | 4.97E-01 | 2.46E-07 | 5.38E-01 | 9.41E-03 |
| Veillonella | 9.04E-07 | 8.04E-01 | 5.27E-01 | 4.81E-07 | 9.89E-01 | 1.76E-02 |
| Collinsella | 2.28E-07 | 9.85E-01 | 2.91E-01 | 6.14E-09 | 5.38E-01 | 1.57E-02 |
| Eubacterium | 1.03E-02 | 1.84E-02 | 5.04E-02 | 1.18E-02 | 2.43E-01 | 2.67E-02 |
For each genus, the FDR-adjusted P -value is shown for each of the three covariates in the model.