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. 2016 Aug 23;65(11):3396–3409. doi: 10.2337/db16-0136

Figure 2.

Figure 2

AFHKO mice are protected against aging-induced obesity. A and B: Growth to 10 months of age in male (A) and female (B) control and AFHKO mice fed a normal diet (n = 12). C: Body composition at 5 months of age (n = 10). Fat percentage refers to fat mass as a fraction of total (lean + fat) mass. D: WAT depot masses and BAT mass of control and AFHKO males at 5 months of age. E: Representative hematoxylin-eosin–stained sections of WAT and BAT from 5-month-old control and AFHKO mice fed a normal chow diet. Scale bar = 100 μm. F: Distribution of white adipocyte diameters in perigonadal WAT (n = 5; ≥315 cells measured/mouse). G: Mean adipocyte diameters. H: Body composition at 10 months of age (n = 8). *P < 0.05; **P < 0.01; ***P < 0.001. BAT, interscapular BAT; Mes, mesenteric; PG, perigonadal; PR, perirenal; SC, subcutaneous.