Table 1.
Characteristics | No. of Participants | % | Mean (SD) |
---|---|---|---|
Offspring Study cohort | 1,024 | 40.8 | |
Age at the time of MDCT scan, years | 52.6 (11.9) | ||
Women | 1,323 | 52.7 | |
Alcohol consumption, drinks/weekb | 3.8 (4.6) | ||
Current cigarette smoker | 307 | 12.2 | |
Former cigarette smoker | 952 | 37.9 | |
Education | |||
High school or less | 580 | 23.1 | |
Some college | 813 | 32.4 | |
College graduate | 1,120 | 44.6 | |
Antihypertensive medication use | 474 | 18.9 | |
Statins use | 314 | 12.5 | |
Cardiovascular disease | 174 | 6.9 | |
Diabetes | 146 | 5.8 | |
Liver-to-phantom ratio | 0.36 (0.05) | ||
Hepatic steatosisc | 436 | 17.4 | |
Annual average PM2.5 concentration (2003), μg/m3 | 10.6 (1.4) | ||
Distance to major roadways, md | 271 (253) | ||
Category of distance to major roadways, md | |||
<50.0 | 514 | 20.5 | |
50.0–99.9 | 213 | 8.5 | |
100.0–199.9 | 396 | 15.8 | |
200.0–399.9 | 518 | 20.6 | |
400.0–999.9 | 589 | 23.4 |
Abbreviations: MDCT, multidetector computed tomography; PM2.5, particulate matter having an aerodynamic diameter of ≤2.5 μm; SD, standard deviation.
a All MDCT scans were conducted between 2002 and 2005. Age and cardiovascular events were updated to the date of MDCT scans; other baseline covariates were collected during 1998–2001 for participants from the Framingham Offspring Study examination 7 and during 2002–2005 for those from the Third Generation Cohort examination 1.
b Standardized to 0.5 oz (15 mL) of alcohol per drink.
c Defined as having a liver-to-phantom ratio of ≤0.33.
d We excluded 283 participants who lived more than 1,000 m from major roadways.