Figure 1.

Odds ratio for use of oral contraceptive pills (OCPs) by quartile of weighted genetic risk score in a simulated analysis of gene-environment interaction and ovarian cancer risk. Data were obtained from 15 studies in the Ovarian Cancer Association Consortium (30, 38–55). The odds ratios were estimated using standard logistic regression with adjustment for history of endometriosis, first-degree family history of ovarian cancer, parity, tubal ligation, age, and study site. Bars, 95% confidence intervals.