Table 1.

Reported cases of Listeria monocytogenes endocarditis.

Case	Age, Sex	Underlying Condition (Including Cardiac Pathology)	Antibiotic Regimen	Valve Type	Medical or Medical + Surgical Treatment	Outcome	Referenceb
1	42, M	Rheumatic Heart Disease, Periodontoclasia	Penicillin + Dihydrostreptomycin + Erythromycin	Native	Medical	Survived	[1]
2	Unknown, F	Severe Anemia	Ciprocinal	Native	Medical	Survived	[2]
3	35, F	Chorea, Septic Abortion	Penicillin + Streptomycin + Erythromycin	Native	Medical	Died	[2]
4	28, M	Rheumatic Heart Disease	Penicillin + Streptomycin	Native	Medical	Survived	[3]
5	55, M	Alcoholism, Metastatic Pancreatic Carcinoma	None	Native	None	Died	[3]
6	40, F	Rheumatic Heart Disease	Oxytetracycline + Streptomycin	Native	Medical	Survived	[4]
7	22, F	Hodgkin’s Lymphoma, Adrenal Insufficiency, Steroid Treatment, Zoster	None	Native	None	Died	[5]
8	49, M	Rheumatic Heart Disease, Diabetes Mellitus, Alcoholism	Penicillin + Streptomycin + Erythromycin (+Isoniazid)	Native	Medical	Died	[6]
9	56, M	Alcoholism, Facial Basal Cell Carcinoma	Penicillin + Erythromycin	Native	Medical	Survived	[7]
10	10, M	Kwashiorkor	Penicillin + Chloramphenicol	Native	Medical	Survived	[8]
11	23, M	Aortic Stenosis	Penicillin + Streptomycin	Native	Medical + Surgical	Died	[9]
12	31, M	Aortic Stenosis	Ampicillin + Streptomycin (Followed By Amphotericin B For Fungal Endocarditis)	Native	Medical + Surgical	Died	[10]
13	64, M	Angina Pectoris	Penicillin + Gentamicin	Native	Medical	Died	[11]
14	32, M	Heart Failure	Chloramphenicol + Oleandomycin + Erythromycin	Native	Medical	Survived	[12]
15	54, M	Unknown	Penicillin + Streptomycin	Native	Unknown	Survived	[13]
16	76, M	Hemolytic Anemia, Autoimmune Radiculitis, Steroid Therapy	None	Native	None	Died	[13]
17	27, F	End Stage Renal Disease, Hemodialysis, Renal Transplant	Ampicillin + Gentamicin	Native	Medical	Survived	[14]
18	69, M	End Stage Renal Disease, Hemodialysis, Renal Transplant, Heart Failure, Myocardial Infarction, Bicuspid Aortic Valve, Atherosclerosis, Hypertension, Angina Pectoris	Ampicillin + Oxacillin	Native	Medical	Died	[14]
19	75, M	Atrial Fibrillation, Heart Failure	Penicillin	Native	Medical	Survived	[15]
20	72, F	Aortic Stenosis, Valve Replacement, Heart Failure	Penicillin + Kanamycin	Prosthetic	Medical + Surgical	Died	[16]
21	64, M	Angina Pectoris	Unknown	Unknown	Unknown	Died	[17]
22	23, M	Aortic Stenosis	Unknown	Native	Unknown	Died	[17]
23	67, F	Rheumatic Heart Disease, Streptococcal Endocarditis, Milroy Disease (Hereditary Lymphedema), Heart Failure, Cellulitis	Cephalothin (First Generation Cephalosporin)	Native	Medical	Died	[18]
24	16, F	Rheumatic Heart Disease	Penicillin	Native	Medical	Survived	[19]
25	55, F	Rheumatic Heart Disease	Penicillin	Native	Medical	Survived	[20]
26	25, F	Pregnancy, Diabetes Mellitus	Ampicillin (For 4 Weeks Then Followed By Amoxicillin For 2 Weeks)	Native	Medical	Survived	[21]
27	64, M	Heart Failure, Valve Replacement	Penicillin	Prosthetic	Medical	Died	[22]
28	53, M	Hypertrophic Cardiomyopathy, Anemia	Penicillin	Native	Medical	Survived	[23]
29	58, F	Rheumatic Heart Disease, Valve Replacement	Penicillin + Tobramycin	Prosthetic	Medical	Survived	[24]
30	23, F	Septic Abortion	Penicillin + Cephalothin + Streptomycin	Native	Medical	Died	[25]
31	Unknown, M	Unknown	Unknown	Unknown	Medical + Surgical	Survived	[26]
32	66, M	Chronic Lymphocytic Leukemia	Penicillin + Streptomycin	Native	Medical	Survived	[27]
33	27, M	Marfan Syndrome, Valve Replacement, Started On Peritoneal Dialysis Over Hospital Course	Penicillin	Prosthetic	Medical	Died	[28]
34	56, F	Mitral Valve Prolapse	Penicillin	Native	Medical	Survived	[29]
35	63, M	Chronic Rectal Fistula, Mitral Stenosis, Valve Replacement	Penicillin + Streptomycin	Prosthetic	Medical	Survived	[30]
36	69, F	Mitral Regurgitation, Valve Replacement	Ampicillin + Gentamicin	Prosthetic	Medical	Survived	[31]
37	34, F	None	Penicillin	Native	Medical	Survived	[32]
38	43, M	Redo Valve Replacement	Ampicillin + Amikacin	Prosthetic	Medical	Died	[33]
39	74, M	Atrial Fibrillation	Ampicillin + Netilmicin (For 3–4 Weeks Followed by Amoxicillin For 4 Weeks)	Native	Medical	Died	[34]
40	68, M	Diabetes Mellitus	Unknown	Unknown	Unknown	Survived	[35]
41	72, F	Unknown	Unknown	Prosthetic	Unknown	Survived	[36]
42	69, F	Myocardial Infarction, Diabetes Mellitus, Hypertension, Heart Failure, Right Iliofemoral Endarterectomy, Arterial Venous Graft, Bilateral Carotid Endarterectomies, Aortic Aneurysm Resection, Aortic Iliac Graft Placement, End Stage Renal Disease, Hemodialysis, Vascular Infection, Vineberg Procedure (Forerunner To CABG)	Vancomycin + Gentamicin	Native	Medical	Survived	[37]
43	77, F	Unknown	Unknown	Unknown	Unknown	Survived	[38]
44	55, M	Myocardial Infarction, Seizure Episode	Penicillin + Netilmicin	Native	Medical + Surgical	Survived	[39]
45	58, M	Colon Adenocarcinoma	Ampicillin + Netilmicin	Native	Medical + Surgical	Died	[40]
46	75, F	Aortic Stenosis, Streptococcal Endocarditis, Lung Adenocarcinoma (Diagnosed During Admission), Colon Adenocarcinoma, Chronic Anemia	Ampicillin + Gentamicin	Native	Medical	Died	[40]
47	83, F	Colon Adenocarcinoma, Atherosclerosis	Ampicillin (Initially Then Pivampicillin)	Native	Medical	Died	[40]
48	52, F	Cirrhosis	Ampicillin + Gentamicin	Native	Medical	Survived	[41]
49	55, M	HIV, Ischemic Heart Disease, Seizures?	Penicillin + Netilmicin	Native	Medical + Surgical	Survived	[42]
50	69, M	Valve Replacement, Rheumatoid Arthritis, Alcoholism	Ampicillin + Streptomycin	Prosthetic	Medical + Surgical	Survived	[43]
51	70, F	Coronary Artery Bypass Graft, Atherosclerosis	Ampicillin + Gentamicin	Native	Medical	Survived	[44]
52	73, F	Valve Replacement, Aortic Insufficiency	Ampicillin + Gentamicin	Prosthetic	Medical + Surgical	Survived	[45]
53	46, M	Valve Replacement	Amoxicillin + Netilmicin	Prosthetic	Medical	Survived	[46]
54	55, Unknown	HIV, Myocardial Infarction	Penicillin + Netilmicin	Native	Medical + Surgical	Survived	[47]
55	35, M	HIV, Intravenous Drug Use, Candida endophthalmitis, Cirrhosis	Co-trimoxazole	Native	Medical	Died	[48]
56	67, M	Valve Replacement, Left Atrial Thrombus, Colon Adenocarcinoma, Mitral Insufficiency	Vancomycin + Gentamicin	Prosthetic	Medical	Survived	[49]
57	78, M	Valve Replacement, Pacemaker, Mitral Regurgitation, Aortic Regurgitation	Ampicillin + Tobramycin	Prosthetic	Medical + Surgical	Survived	[50]
58	56, F	Valve Replacement	Co-trimoxazole	Prosthetic	Medical + Surgical	Survived	[51]
59	71, M	Valve Replacement, Vertebral Fracture, Spondylodiscitis	Ampicillin + Amikacin	Prosthetic	Medical + Surgical	Survived	[52]
60	61, M	Rheumatic Heart Disease, Valve Replacement	Ampicillin + Gentamicin	Prosthetic	Medical	Survived	[53]
61	69, M	Valve Replacement, Colon Adenocarcinoma, Multiple Bouts of Endocarditis (E. faecalis, S. sanguis, K. pneumoniae), Mitral Valvuloplasty	Vancomycin + Gentamicin	Prosthetic	Medical	Survived	[54]
62	78, F	Valve Replacement	Ampicillin	Prosthetic	Medical	Survived	[55]
63	65, M	Hemachromatosis, Duodenal Ulcer, Laparotomy	Ampicillin + Tobramycin	Native	Medical	Died	[56]
64	67, M	Alcoholism, Valve Replacement	Ampicillin + Gentamicin	Prosthetic	Medical + Surgical	Survived	[57]
65	76, F	Urinary Tract Infection, Valve Replacement	Ampicillin + Gentamicin	Prosthetic	Medical	Died	[58]
66	41, F	Liver Transplant, Immunosuppressive Therapy, CMV Hepatitis, Hickman’s Catheter	Ampicillin (Followed By Penicillin) + Gentamicin	Native	Medical	Survived	[59]
67	74, M	Varicose Vein Stripping, Valve Replacement	Amoxicillin + Gentamicin	Prosthetic	Medical + Surgical	Survived	[60]
68	79, M	Hepatitis B Virus, Valve Replacement	Ampicillin + Gentamicin	Prosthetic	Medical + Surgical	Survived	[61]
69	69, F	Valvuloplasty, Valve Replacement, Pacemaker	Ampicillin (For 3 Weeks Then Co-trimoxazole + Rifampicin + Teicoplanin For 4–5 Weeks)	Prosthetic	Medical	Survived	[62]
70	42, M	HIV, Diabetes Mellitus, Chronic Renal Failure, Heart Failure, Redo Valve Replacement	Ampicillin + Gentamicin	Prosthetic	Medical	Survived	[63]
71	81, M	Valve Replacement	Ampicillin + Gentamicin (Then Lifelong Suppressive Therapy With Amoxicillin)	Prosthetic	Medical + Surgical	Survived	[64]
72	77, M	Rheumatic Heart Disease, Valve Replacement	Vancomycin + Gentamicin	Prosthetic	Medical + Surgical	Survived	[65]
73	68, M	Rheumatic Heart Disease, Valve Replacement	Penicillin + Gentamicin	Prosthetic	Medical + Surgical	Survived	[65]
74	70, M	Aortic Stenosis, Colon Polyp	Ampicillin + Gentamicin (Stopped After 7 Days Due To Renal Insufficiency)	Native	Medical + Surgical	Survived	[66]
75	76, M	Valve Replacement, Defibrillator, Chronic Renal Insufficiency, Polymyalgia Rheumatica, Barrett’s Esophagus, GERD, Chronic Gastritis, Diverticulosis, Colon Polyp, Duodenal Ulcer, Iron Deficiency Anemia, Transient Ischemic Attack	Vancomycin (For 2 Weeks Then Linezolid For 4 Weeks)	Prosthetic	Medical + Surgical	Survived	[67]
76	76, M	Hypertension, Hyperlipidemia, Coronary Artery Bypass Graft, Valve Replacement, Tobacco Use, Invasive Rectal Carcinoma	Unknown	Prosthetic	Medical + Surgical	Died	[68]
77	74, M	Valve Replacement, Aortic Stenosis	Meropenem + Gentamicin	Prosthetic	Medical	Survived	[69]
78	71, M	Hypertension, Atherosclerosis, Alcoholism, Alcoholic Hepatitis, Chronic Renal Insufficiency, Tobacco Use, Dental Procedure	Penicillin	Native	Medical	Survived	[70]
79	80, F	Listeria Meningitis (1 Year Prior), Valve Replacements (Mitral + Aortic)	Ampicillin + Gentamicin	Prosthetic	Unknown	Unknown	[71]
80	73, F	Diabetes Mellitus, Valve Replacement	Co-trimoxazole + Aminoglycoside (Type Unknown)	Prosthetic	Unknown	Unknown	[71]
81	87, M	Valve Replacement, Atrial Fibrillation, Heart Failure, Prostate Cancer, Hemorrhoids	Ampicillin (6 Weeks) + Tobramycin (3 Weeks) (Followed By Amoxicillin For 9 Weeks)	Prosthetic	Medical	Survived	[72]
82	67, M	Valve Replacement	Linezolid + Co-trimoxazole	Prosthetic	Medical + Surgical	Survived	[73]
83	5, M	None	Levofloxacin + Rifampin	N/Aa	Medical + Surgical	Survived	[74]
84	78, F	3rd Degree Heart Block, Pacemaker, Heart Failure, Tricuspid Regurgitation, Coronary Artery Bypass Graft, Hypoglycemia	Ampicillin + Gentamicin	Native	Medical	Died	[75]
85	42, F	Psoriatic Arthritis On Infliximab	Ampicillin	Native	Medical	Survived	[76]
86	74, M	HIV	Unknown	N/Aa	Medical + Surgical	Survived	[77]
87	74, M	Rheumatic Heart Disease, Atrial Fibrillation, Atrophic Gastritis	Ampicillin + Gentamicin	Native	Medical + Surgical	Died	[78]
88	58, F	Rheumatic Heart Disease, Valvuloplasties, Valve Replacement, Atrial Fibrillation, Chronic Renal Insufficiency, Right Nephrectomy	Ampicillin + Gentamicin	Prosthetic	Medical + Surgical	Died	[78]
89	44, F	Multiple Sclerosis	Amoxicillin + Gentamicin	N/Aa	Medical + Surgical	Survived	[79]
90	77, M	Coarctation of the Aorta, Valve Replacements (Mitral + Aortic), Hypertension, Heart Failure, Hypothyroidism	Ampicillin + Gentamicin	Prosthetic	Medical	Survived	[80]
91	73, F	Breast Cancer With Metastases, Diabetes Mellitus	Ampicillin + Gentamicin	N/Aa	Medical	Survived	[81]
92	70, M	Valve Replacement, Aortic Stenosis, Atrial Fibrillation, Pacemaker, Diabetes Mellitus, Cerebrovascular Accident, Rheumatoid Arthritis on Methotrexate, Chronic Obstructive Pulmonary Disease	Meropenem + Ciprofloxacin	Native	Medical	Died	[82]
93	54, F	None	Amoxicillin + Gentamicin + Co-trimoxazole	Native	Medical	Survived	[83]
94	54, M	Congenitally Corrected Transposition of the Great Vessels, Valve Replacements (Mitral + Aortic)	Ampicillin + Gentamicin	Prosthetic	Medical	Survived	[84]
95	36, F	Pregnancy, Bicuspid Aortic Valve	Ampicillin + Gentamicin	Native	Medical + Surgical	Survived	[85]
96	84, M	Chronic Renal Failure, Diabetes Mellitus, Collagenopathy, Chronic Corticosteroid Use, Valve Replacement	Meropenem + Daptomycin	Prosthetic	Medical	Survived	[86]
97	84, M	Valve Replacement	Ampicillin + Gentamicin	Prosthetic	Medical	Survived	[86]
98	80, F	Diabetes Mellitus, Valve Replacement	Ampicillin + Gentamicin	Prosthetic	Medical	Survived	[86]
99	79, M	Diabetes Mellitus, Valve Replacement	Ampicillin + Gentamicin	Native	Medical	Survived	[86]
100	63, M	Hypertension, Diabetes Mellitus, Atrial Flutter, Valve Replacement	Penicillin + Rifampicin (For 4–6 Weeks Then Amoxicillin For 18 Weeks)	Prosthetic	Medical + Surgical	Survived	[87]

^aMass/Vegetation Identified Along Right Atrium, Left Atrium And/Or Left Ventricular Outflow Tract.

^bPlease see supplementary data section for table references.