Table 4. Cardiovascular events avoided over 5 y for the same number of persons treated using selected SBP thresholds and corresponding CVD risk thresholds.
The BPLTTC (n = 47,872).
| SBP threshold | ||||
|---|---|---|---|---|
| 140 mmHg | 150 mmHg | 160 mmHg | ||
| n = 39,231 | n = 33,891 | n = 27,039 | ||
| CVD events avoided using an SBP threshold | n | 821 (819 to 821) | 698 (692 to 716) | 557 (544 to 599) |
| CVD events avoided using a CVD risk threshold selected to achieve the same number of persons treated | n | 847 (833 to 860) | 809 (795 to 822) | 767 (755 to 776) |
| Difference and relative difference in CVD events avoided using SBP and CVD risk thresholds selected to achieve the same number of persons treated | n | +26 (+12 to +41) | +111 (+97 to +127) | +210 (175 to 222) |
| percentage | +3.1 (+1.5 to +5.0) | +15.8 (+13.7 to +18.3) | +37.6 (+28.8 to +40.2) | |
Estimates with 10,000 repetitions bias-corrected bootstrap with 95% CIs in parentheses. Negative sign represents smaller proportion or lesser number. Positive sign represents greater number.
Abbreviations: BPLTTC, Blood Pressure Lowering Treatment Trialists’ Collaboration; CI, confidence interval; CVD, cardiovascular disease; SBP, systolic blood pressure.