Table 3. Drug resistance gene distribution among the molecular types of 41 CR-KP isolates from pediatric patients.
| Sequence type | Isolates | Carbapenemase | Penicllinases and Extended-spectrum β-lactamase | AmpC β-lactamase | 16S rRNA methylase | PMQR genes |
|---|---|---|---|---|---|---|
| ST11 | 8 | KPC-2(8) | TEM-1(8),SHV11(8),CTX M-14(8) | rmtB(8) | oqxAB(5) | |
| ST25 | 6 | NDM-1(6) | TEM-1(6),SHV11(6),CTX M-15(6) | oqxAB(6) | ||
| ST76 | 6 | NDM-1(6) | TEM-1(2),SHV11(6),CTX M-14(2) | DHA-1(4) | armA(1) | aac(1),oqxAB(6),qnrB4(4) |
| ST37 | 4 | IMP-4(2),NDM-1(2) | TEM-1(1),SHV11(4),CTX M-15(1),CTX M-14(4) | aac(2),oqxAB(4),qnrS1(3) | ||
| ST17 | 3 | NDM-1(3) | TEM-1(2),SHV11(3),CTX M-15(1),CTX M-14(1) | DHA-1(1) | oqxAB(4),qnrS1(1),qnrB4(1) | |
| ST45 | 2 | KPC-2(1),NDM-1(1) | SHV1(1),SHV11(1),CTX M-15(1) | oqxAB(2) | ||
| ST334 | 2 | IMP-4(2),NDM-1(2) | TEM-1(2),OXA-1(2) | aac(2) | ||
| ST20 | 2 | IMP-4(2) | TEM-1(1),SHV11(2),CTX M-15(1),CTX M-14(1) | aac(2),oqxAB(2),qnrS1(2) | ||
| ST278 | 1 | IMP-4(1) | TEM-1(1),SHV27(2),OXA-1(1) | aac(1),oqxAB(1) | ||
| ST414 | 1 | NDM-1(2) | TEM-1(1),SHV11(1),CTX M-15(1) | |||
| ST147 | 1 | IMP-4(1) | TEM-1(1),SHV11(1),CTX M-15(1) | oqxAB(1) | ||
| ST1198 | 1 | NDM-1(1) | SHV11(1),CTX M-14(1) | DHA-1(1) | oqxAB(1),qnrS(1),qnrB4(1) | |
| ST14 | 1 | IMP-4(1) | TEM-1(1),SHV1(1),OXA-1(1),CTX M-15(1) | aac(1),oqxAB(1) | ||
| ST1699 | 1 | NDM-1(1) | SHV11(1),OXA-1(1) | aac(1),oqxAB(1),qnrS1(1) | ||
| ST1822 | 1 | IMP-8(1) | TEM-1(1),CTX M-15(1) | armA(1) | aac(1),oqxAB(1) | |
| SLV of ST156 | 1 | IMP-4(1) | TEM-1(1),SHV11(1),OXA-1(1) | aac(1),oqxAB(1) |
aac: aac(6’)-Ib-cr
PMQR: plasmid-encoded quinolone resistance-associated genes