Skip to main content
. 2018 Mar 20;13(3):e0194701. doi: 10.1371/journal.pone.0194701

Table 1. Interpretation of gene expression levels.

KEGG Pathways
Up-regulated Down-regulated
Pathway P-value Pathway P-value
Base excision repair 0 NOD like receptor signaling pathway 0.0325
Thyroid cancer 0
RNA polymerase 0.0055
Endometrial cancer 0.0068
N glycan biosynthesis 0.0132
Adherens junction 0.0138
Pyrimidine metabolism 0.0268
Nucleotide excision repair 0.0323
Non small cell lung cancer 0.0337
Galactose metabolism 0.0491

Gene Ontology Biological Processes
Up-regulated Down-regulated
Process P-value Process P-value
Positive regulation of phosphate metabolic process 0.0074 Cell maturation 0.0081
Insulin receptor signaling pathway 0.0087 Developmental maturation 0.0084
RNA export from nucleus 0.0111 Cell migration 0.0099
Transmembrane receptor protein tyrosine kinase signaling pathway 0.0112 Negative regulation of map kinase activity 0.0111
Base excision repair 0.0123 Muscle development 0.0143
Cellular protein complex assembly 0.0133 Rhythmic process 0.0195
Transcription initiation from RNA polymerase ii promoter 0.0134 Microtubule based movement 0.0196
Protein amino acid n linked glycosylation 0.0136 Regulation of biological quality 0.0197
Nuclear export 0.0152 Cell development 0.0203
Protein complex assembly 0.0159 Synaptic transmission 0.0209
Regulation of protein modification process 0.0167 Nervous system development 0.0217
Mitochondrion organization and biogenesis 0.0206 Regulation of action potential 0.0219
Nucleotide excision repair 0.0223 Muscle cell differentiation 0.0225
Stress activated protein kinase signaling pathway 0.0248 Myoblast differentiation 0.0228
Positive regulation of protein modification process 0.0261 Cytoskeleton dependent intracellular transport 0.0264
Carbohydrate metabolic process 0.0268 Negative regulation of cell differentiation 0.0297
Positive regulation of protein metabolic process 0.0269 Behavior 0.0309
Macromolecular complex assembly 0.0270 Protein homooligomerization 0.0325
Cellular component assembly 0.0336 Transmission of nerve impulse 0.035
JNK cascade 0.0358 Central nervous system development 0.0352
DNA repair 0.0361 Regulation of g protein coupled receptor protein signaling pathway 0.0374
Carbohydrate catabolic process 0.0363 Skeletal muscle development 0.0384
Cellular carbohydrate catabolic process 0.0363 Cell proliferation go 0008283 0.0386
Transcription initiation 0.0401 Locomotory behavior 0.0493
Interaction with host 0.0449
Nucleobasenucleosidenucleotide and nucleic acid transport 0.0455
Positive regulation of metabolic process 0.0465
Regulation of protein amino acid phosphorylation 0.0479
Golgi vesicle transport 0.0486
Glycoprotein metabolic process 0.0493
Positive regulation of phosphorylation 0.0495