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. 2018 Mar 20;13(3):e0194468. doi: 10.1371/journal.pone.0194468

Fig 2. The change in blood glucose after insulin dosing during dark and light periods.

Fig 2

The blood glucose lowering effect of 86 nmol/kg insulin compared to 120 nmol/kg insulin during light (A and B) and dark period (C and D), respectively. The change in blood glucose plotted as a function of time (A and C). The maximum change from baseline (B and D). Data are expressed as means of 5 days (86 nmol/kg) and 2 days (120 nmol/kg), respectively ± SEM; n = 7–8. A significant difference between 86 and 120 nmol/kg insulin during the light period and dark period is indicated by ** (p = 0.001) and * (p = 0.03), respectively. (analyzed using a two-tailed paired t-test).