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. 2018 Mar 20;13(3):e0194435. doi: 10.1371/journal.pone.0194435

Table 2. PET/CT imaging and interpretation methods.

Study reference Post injection
interval (min)
FDG dose
(MBq/kg)
parameters Cut-off values Interpreters Time interval before I-PET Time interval before E-PET
SUVmax MTV (mL) TLG (g)
Jiang et al, 2017 [21] 60 5.18 E-PET/CT DS 2 physicians specializing in nuclear medicine During the 4 weeks after initial treatment 3 weeks after the
end of treatment
Chang et al, 2017 [22] 60±15 3.7–4.4 B-PET/CT SUVmax, MTV and TLG 15.1 16.1 44.7 2 experienced nuclear medicine physicians Median 19.0 days (after 2–4 cycles of chemotherapy) Median 31.5 days
Liang et al, 2016 [23] 60 3.70–5.55 B-PET/CT SUVmax 15.8 NR NR NR
Lim et al, 2016 [24] NR NR I-PET/CT DS 1 nuclear medicine physician NR NR
Jiang et al, 2015 [25] 60 5.18 I-PET/CT DS 2 physicians specializing in nuclear medicine 3 weeks (after 2 cycles of therapy) NR
Kim et al, 2015 [26] 60±10 5.5 E-PET/CT DS 1 experienced nuclear medicine physician NR At least 4 weeks after treatment
Kim et al, 2013 [27] 60 8.1 B-PET/CT SUVmax, MTV and TLG 8.1 14.4 52.7 NR NR NR
Bai et al, 2013 [28] 60 4.4 B-PET/CT SUVmax 15 2 experienced nuclear medicine physicians NR NR
Song et al, 2013 [29] NR NR B-PET/CT MTV 35.2 1 nuclear medicine expert NR NR

NR, not reported.