Table 1. Demographic and clinical characteristics of HIV+ persons and frequency-matched controls.
| HIV+ (N = 5052) | Controls (N = 10121) | P-value | ||
|---|---|---|---|---|
| Age (years) | 48.2 ± 11.6 | 48.2 ± 11.4 | 0.68 | |
| 18–30, N (%) | 331 (6.6%) | 647 (6.4%) | 0.98 | |
| 31–40 | 921 (18.3%) | 1871 (18.5%) | ||
| 41–50 | 1451 (28.8%) | 2886 (28.5%) | ||
| 51–60 | 1615 (32.0%) | 3291 (32.5%) | ||
| 61–70 | 590 (11.7%) | 1159 (11.4%) | ||
| >70 | 133 (2.6%) | 267 (2.6%) | ||
| Race (N, %) | <0.01 | |||
| White | 1680 (34.5%) | 3207 (39.9%) | ||
| Black | 1573 (32.3%) | 2698 (33.5%) | ||
| Hispanic | 173 (3.6%) | 359 (4.5%) | ||
| Other/Unknown | 1438 (29.6%) | 1783 (22.2%) | ||
| Male (N, %) | 4167 (82.5%) | 8381 (82.8%) | 0.13 | |
| Body-Mass Index (kg/m2) | 25.9 ± 5.6 | 28.6 ± 6.5 | <0.01 | |
| Total cholesterol (mg/dl) | 202.2 ± 59.1 | 194.5 ± 50.6 | <0.01 | |
| HDL cholesterol (mg/dl) | 34.3 ± 13.1 | 42.9 ± 14.1 | <0.01 | |
| Hepatitis C Virus (N, %) | 425 (8.4%) | 90 (0.9%) | <0.01 | |
| Hypertension (N, %) | 1674 (33.1%) | 1893 (18.7%) | <0.01 | |
| Diabetes (N, %) | 463 (9.2%) | 603 (6.0%) | <0.01 | |
| Coronary Heart Disease (N, %) | 728 (14.4%) | 704 (7.0%) | <0.01 | |
| Myocardial Infarction (N, %) | 571 (11.3%) | 502 (5.0%) | <0.01 | |
| Chronic Obstructive Pulmonary Disease (N, %) | 305 (6.0%) | 223 (2.2%) | <0.01 | |
| Stroke, N (%) | 316 (6.3%) | 281 (2.8%) | <0.01 | |
| Atrial Fibrillation (N, %) | 101 (2.00%) | 159 (1.57%) | 0.056 | |
| CHADS Score (N, %) | <0.01 | |||
| 0 | 2915 (57.8%) | 7784 (76.9%) | ||
| 1 | 1213 (24.1%) | 1354 (13.4%) | ||
| 2 | 509 (10.1%) | 601 (5.9%) | ||
| 3 | 226 (4.5%) | 220 (2.2%) | ||
| 4 | 125 (2.5%) | 100 (1.0%) | ||
| 5 | 47 (0.9%) | 54 (0.5%) | ||
| 6 | 6 (0.1%) | 8 (0.1%) | ||
| CHADS Score <2 (N, %) | 4128 (81.9%) | 9138 (90.3%) | <0.01 | |
Note: Continuous variables compared with t-test or nonparametric equivalent; Categorical variables compared with chi-square or nonparametric equivalent; Total cholesterol and HDL cholesterol calculated as peak and nadir, respectively, given several measurements over time