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. Author manuscript; available in PMC: 2018 Mar 20.
Published in final edited form as: Cell Rep. 2018 Feb 20;22(8):2133–2145. doi: 10.1016/j.celrep.2018.01.074

Figure 3. Loss of MiR-33 Increases Liver Triglyceride and Diacylglycerol Content and PKCε Activation.

Figure 3

(A–C) Liver triglyceride (TAGs) (A), diacylglycerol (DAGs) (B), and ceramide content (C) in WT and miR-33−/− mice fed a chow diet (CD) for 20 weeks after overnight feeding (n = 6–7).

(D) Western blot analysis of PKCε translocation in WT and miR-33−/− mice fed a CD for 20 weeks after overnight feeding. GAPDH and ATPase were used as loading controls for cytosolic and membrane fractions respectively. Quantification is shown in right panels (n = 6–7). All data represent the mean ± SEM, and an asterisk indicates p < 0.05 comparing miR-33−/− with WT mice on the same diet.