Table 1.
Subject characteristics, transplant history, diabetes medications, and causes of death
| Non-CF (younger) | Non-CF (older) | CF-no DM | CFRD | |
|---|---|---|---|---|
| N | 20 | 20 | 17 | 18 |
| Age (years) | 13.1 ± 6.8 | 28.0 ± 5.5*# | 13.9 ± 8.3 | 28.6 ± 9.0*# |
| Sex (female/male) | 12/8 | 9/11 | 12/5 | 10/8 |
| BMI (kg/m2) | 19.8 ± 7.0 | 22.6 ± 5.5# | 16.5 ± 3.9 | 21.7 ± 3.3# |
| Diabetes duration (years) (n = 17) | 4.80 ± 5.16 | |||
| HbA1c (%) (n = 11) | 7.25 ± 1.67 | |||
| Lung transplant (yes/no/unknown) | 0/19/0 | 0/20/0 | 4/13/0 | 10/6/2 |
| Other transplant | 1 (heart) | 0 | 0 | 0 |
| Diabetes medications | ||||
| Oral agent | 1 | |||
| Insulin | 16 | |||
| Unknown | 2 | |||
| Steroid use (yes/no/unknown) | 4/13/3 | 0/15/5 | 4/13/0 | 11/5/2 |
| Pancreatic enzyme supplementation (yes/no/unknown) | 16/0/1 | 16/0/2 | ||
| Cause of death | ||||
| Respiratory | 5 | 5 | 14 | 14 |
| Cardiovascular | 4 | 4 | 2 | — |
| CNS | 3 | 6 | — | — |
| Infection | 4 | 3 | — | — |
| Malignancy | 2 | — | — | — |
| Multiorgan failure | 1 | 2 | — | 3 |
| Unknown | 1 | — | — | 1 |
Data are means ± SD or n. CNS, central nervous system.
*P < 0.05 vs. non-CF (younger).
#P < 0.05 vs. CF-no DM.