Table 2.

Current night shift work and type 2 diabetes odds in the UK Biobank (N = 272,214)

	Current night shift work
	Day workers	Shift work, but never or rarely night shifts	Irregular, rotating shifts with some night shifts	Irregular, rotating shifts with usual night shifts	Permanent night shift work
Total cases	5,173	730	461	169	237
Total sample size	224,928	23,172	13,559	3,754	6,801
Model 1: age- and sex-adjusted OR (95% CI)	1.00	1.43 (1.32–1.55)	1.54 (1.39–1.70)	2.10 (1.79–2.46)	1.58 (1.38–1.80)
Model 2: multivariable-adjusted OR (95% CI)*	1.00	1.15 (1.05–1.26)	1.18 (1.05–1.32)	1.44 (1.19–1.73)	1.09 (0.93–1.27)
Model 3: + BMI OR (95% CI)	1.00	1.11 (1.02–1.22)	1.13 (1.01–1.22)	1.37 (1.13–1.65)	1.09 (0.93–1.27)

*Additionally adjusted for ethnicity, family history of type 2 diabetes, alcohol consumption, Townsend Deprivation Index, physical activity, hypertension, antihypertensive medication use, elevated cholesterol levels, and lipid-lowering and statin medication use.