Table 4.
Association of average lifetime number of night shifts worked across all reported jobs and type 2 diabetes odds (N = 70,480)
| Average lifetime night shift frequency |
P for trend | ||||
|---|---|---|---|---|---|
| None | <3/month | 3–8/month | >8/month | ||
| Total cases | 804 | 52 | 125 | 210 | |
| Total sample size | 52,782 | 2,209 | 6,844 | 7,454 | |
| Model 1: age- and sex-adjusted OR (95% CI) | 1.00 | 1.35 (1.01–1.78) | 1.21 (1.00–1.46) | 1.66 (1.41–1.93) | <0.001 |
| Model 2: multivariable-adjusted OR (95% CI)* | 1.00 | 1.24 (0.90–1.68) | 1.11 (0.90–1.37) | 1.36 (1.14–1.62) | 0.001 |
| Model 3: + BMI OR (95% CI) | 1.00 | 1.16 (0.83–1.58) | 1.02 (0.82–1.26) | 1.21 (1.02–1.45) | 0.08 |
*Additionally adjusted for ethnicity, family history of type 2 diabetes, alcohol consumption, Townsend Deprivation Index, physical activity, hypertension, antihypertensive medication use, elevated cholesterol levels, and lipid-lowering and statin medication use.