Table 3.

Crude and age-standardized 5-year mortality risk in the U.S. adult population with diabetes by time period and by CKD phenotype

	1988–1994 population estimate = 13.2 million	1999–2002 population estimate = 16.0 million	2003–2006 population estimate = 19.7 million
Crude mortality risk (95% CI)+
eGFR ≥90 mL/min/1.73 m2
ACR (mg/g)
<30	5.6 (2.9, 8.3)	5.0 (0.9, 9.1)	3.8 (1.3, 6.3)
30–299	5.5 (0.4, 10.6)	10.1 (1.7, 18.5)	7.0 (3.7, 12.3)
≥300	4.9++	2.3++	8.8++
eGFR 60–89 mL/min/1.73 m2
ACR (mg/g)
<30	11.8 (8.7, 14.9)	7.5 (4.0, 11.0)	7.2 (3.7, 10.7)
30–299	19.1 (11.1, 27.1)	14.2 (5.0, 23.4)	18.6 (11.2, 26.0)
≥300	34.6 (21.2, 47.9)	28.9 (4.4, 53.4)	14.4 (0.7, 27.7)
eGFR <60 mL/min/1.73 m2
ACR (mg/g)
<30	16.3 (9.4, 23.2)	23.2 (12.4, 34.0)	22.8 (13.2, 32.4)
30–299	46.4 (33.9,58.9)	40.0 (23.9, 56.1)	33.5 (20.2, 46.8)
≥300	44.7 (25.1, 64.3)	43.7 (27.6, 62.7)	29.8 (18.4, 41.2)
Age-standardized mortality risk (95% CI)*
eGFR ≥90 mL/min/1.73 m2
ACR (mg/g)
<30	10.0 (6.3, 13.7)	12.2 (5.9, 18.5)	11.2 (7.5, 14.9)
30–299	5.4 (1.9, 8.9)	18.4 (13.3, 23.5)	10.8 (7.5, 14.1)
≥300	12.0 (4.9, 19.1)	7.7++	10.0 (7.1, 12.9)
eGFR 60–89 mL/min/1.73 m2
ACR (mg/g)
<30	9.6 (7.1, 12.1)	8.2 (3.9, 12.5)	6.8 (3.9, 9.7)
30–299	13.3 (8.8, 17.8)	15.9 (6.9, 24.9)	11.9 (7.0, 16.8)
≥300	29.4 (19.6, 39.2)	21.2 (10.6, 31.8)	25.9 (16.9, 34.9)
eGFR <60 mL/min/1.73 m2
ACR (mg/g)
<30	6.2 (3.7, 8.7)	18.3 (6.9, 29.7)	20.9 (10.5, 26.2)
30–299	37.0 (25.0, 49.0)	39.6 (27.6, 51.6)	23.8 (13.0, 34.6)
≥300	43.1 (29.8, 56.4)	51.1 (38.4, 63.8)	28.9 (16.4, 41.4)

The CKD-EPI equation was used to calculate eGFR (15).

+Percentage who died within 5 years.

*Populations age standardized to U.S. population in 2000.

++Sample size was too small to determine stable estimate of deaths.