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. Author manuscript; available in PMC: 2018 Jul 11.
Published in final edited form as: Oncogene. 2018 Jan 11;37(12):1561–1575. doi: 10.1038/s41388-017-0045-7

Table 1.

Mutations of EGFR and related pathways in GBM

“Percentage” indicates frequencies of mutations in GBM patients.

GENE Symbol Chromosomal location Alteration Percentage
EGFR Ch 7p Amplification/mutation 57.4
11.8 with EGFRvIII
p110α Ch 3q Mutation 18.3
p85α Ch 5q Mutation 6.8
PTEN Ch 10q Mutation/deletion 34.3
NF1 Ch 17q Mutation/deletion 10