. Author manuscript; available in PMC: 2018 Jul 11.

Published in final edited form as: Oncogene. 2018 Jan 11;37(12):1561–1575. doi: 10.1038/s41388-017-0045-7

Table 1.

Mutations of EGFR and related pathways in GBM

“Percentage” indicates frequencies of mutations in GBM patients.

GENE Symbol	Chromosomal location	Alteration	Percentage
EGFR	Ch 7p	Amplification/mutation	57.4
EGFR	Ch 7p	Amplification/mutation	11.8 with EGFRvIII
p110α	Ch 3q	Mutation	18.3
p85α	Ch 5q	Mutation	6.8
PTEN	Ch 10q	Mutation/deletion	34.3
NF1	Ch 17q	Mutation/deletion	10