TABLE 3.

Morphological Analysis of Apical and Basal Dendrites in CA3

Cell types and measurements	Salinea	MTX+AraCa	P value
CA3 apical
Thin spines (no.)	53.21 ± 1.89	54.87 ± 3.75	p = 0.46
Stubby spines (no.)	34.74 ± 1.20	37.6 ± 3.93	p = 0.33
Mushroom spines (no.)	12.06 ±1.04	7.59 ± 0.24	p = 0.05
Overall density (no.)	20.18 ± 0.28	20.90 ± 0.77	p = 0.18
Total dendritic length (µm)	844.9 ± 50.72	557.2 ± 63.10	p = 0.11
Total branch points (no.)	7.68 ± 0.26	6.75 ± 0.63	p = 0.39
Total branch tips (no.)	9.08 ± 0.32	8.45 ± 0.86	p = 0.69
Dendritic complexity	29209 ± 3570	13227 ± 1951	p < 0.05
CA3 basal
Thin spines (no.)	51.39 ± 1.35	50.11 ± 1.62	p = 0.70
Stubby spines (no.)	36.64 ± 0.81	41.06 ± 0.87	p = 0.15
Mushroom spines (no.)	11.97 ± 0.76	8.84 ± 0.82	p < 0.05
Overall density (no.)	20.51 ± 0.25	19.63 ± 0.95	p = 0.25
Total dendritic length (µm)	1200 ± 96.61	777.3 ± 81.67	p = 0.35
Total branch points (no.)	10.48 ± 0.71	8.35 ± 0.70	p = 0.35
Total branch tips (no.)	13.68 ± 0.87	11.60 ± 0.58	p = 0.29
Dendritic complexity	24122 ± 5107	11890 ± 2978	p < 0.05

^aMean ± SEM.

^bValues in boldface are significant.