Appendix Table.
Means, standard errors, and 99% confidence intervals from analysis of covariance.
| Region | Bregma Level | Group | Mean | Std. Error | 99% Confidence Interval | |
|---|---|---|---|---|---|---|
| Lower | Upper | |||||
| Infralimbic cortex, dorsal (ILd) | 1.98 mm | Acquisition | 320.1 | 18.0 | 270.4 | 369.8 |
| Extinction, 1 | 371.5 | 18.0 | 321.7 | 421.3 | ||
| Control | 300.8 | 19.3 | 247.5 | 354.1 | ||
| Infralimbic cortex, ventral (ILv) | 1.98 mm | Acquisition | 304.8 | 14.8 | 263.9 | 345.7 |
| Extinction, 1 | 348.2 | 14.8 | 307.2 | 389.2 | ||
| Control | 288.5 | 15.9 | 244.7 | 332.4 | ||
| Anterior habenula (HBa) | −0.82 mm | Acquisition, 2 | 320.2 | 20.9 | 262.4 | 377.9 |
| Extinction | 248.0 | 21.0 | 190.1 | 305.9 | ||
| Control | 287.7 | 22.4 | 225.8 | 349.7 | ||
| Nucleus reunions | −0.82 mm | Acquisition | 324.4 | 17.9 | 274.9 | 373.8 |
| Extinction | 300.2 | 18.0 | 250.6 | 349.8 | ||
| Control | 275.4 | 19.2 | 222.3 | 328.5 | ||
| Paraventricular hypothalamus | −0.82 mm | Acquisition | 257.0 | 10.8 | 227.2 | 286.8 |
| Extinction | 238.3 | 10.8 | 208.5 | 268.2 | ||
| Control | 230.1 | 11.6 | 198.1 | 262.0 | ||
| Amygdala, lateral nucleus (LA) | −1.58 mm | Acquisition | 295.0 | 18.3 | 244.3 | 345.8 |
| Extinction | 290.1 | 17.3 | 242.2 | 338.0 | ||
| Control | 252.2 | 18.8 | 200.2 | 304.1 | ||
| Amygdala, basolateral nucleus (BLA) | −1.58 mm | Acquisition | 294.6 | 15.7 | 251.1 | 338.1 |
| Extinction | 302.5 | 14.8 | 261.4 | 343.5 | ||
| Control | 280.0 | 16.1 | 235.5 | 324.5 | ||
| Amygdala, centrolateral nucleus (CeL) | −1.58 mm | Acquisition | 252.9 | 18.4 | 202.1 | 303.8 |
| Extinction | 252.9 | 17.3 | 204.9 | 300.9 | ||
| Control | 218.3 | 18.8 | 166.3 | 270.4 | ||
| Amygdala, centromedial nucleus (CeM) | −1.58 mm | Acquisition, 3 | 260.5 | 12.8 | 225.0 | 296.1 |
| Extinction | 239.6 | 12.1 | 206.0 | 273.1 | ||
| Control | 222.8 | 13.1 | 186.4 | 259.2 | ||
| Amygdala, intercalated cells, dorsal (ITCd) | −1.58 mm | Acquisition | 274.8 | 18.7 | 223.0 | 326.5 |
| Extinction | 273.6 | 17.6 | 224.7 | 322.4 | ||
| Control | 239.9 | 19.1 | 186.9 | 292.9 | ||
| Amygdala, intercalated cells, ventral (ITCv) | −1.58 mm | Acquisition | 286.6 | 13.0 | 250.6 | 322.6 |
| Extinction | 271.8 | 12.3 | 237.8 | 305.7 | ||
| Control | 258.5 | 13.3 | 221.7 | 295.4 | ||
| Posterior habenula, lateral (HBl) | −1.58 mm | Acquisition | 435.2 | 22.2 | 373.8 | 496.5 |
| Extinction | 376.0 | 22.3 | 314.5 | 437.6 | ||
| Control | 401.7 | 23.8 | 335.9 | 467.5 | ||
| Posterior habenula, medial (HBm) | −1.58 mm | Acquisition, 2 | 384.0 | 18.8 | 332.1 | 436.0 |
| Extinction | 319.3 | 18.8 | 267.2 | 371.4 | ||
| Control | 335.9 | 20.2 | 280.2 | 391.7 | ||
| Periaqueductal gray, anterior | −3.08 mm | Acquisition | 353.9 | 15.9 | 309.8 | 398.0 |
| Extinction | 354.6 | 16.0 | 310.5 | 398.8 | ||
| Control | 312.7 | 17.1 | 265.5 | 360.0 | ||
| Posterior thalamus | −3.08 mm | Acquisition | 375.9 | 14.5 | 335.7 | 416.1 |
| Extinction | 367.0 | 14.6 | 326.7 | 407.3 | ||
| Control | 353.0 | 15.6 | 309.9 | 396.1 | ||
| Posterior intralaminar nucleus | −3.08 mm | Acquisition | 370.8 | 15.1 | 329.1 | 412.6 |
| Extinction | 358.9 | 15.1 | 317.1 | 400.7 | ||
| Control | 346.2 | 16.2 | 301.5 | 391.0 | ||
| Dorsomedial periaqueductal gray (DMPAG) | −4.72 mm | Acquisition, 3 | 286.4 | 10.3 | 258.0 | 314.8 |
| Extinction | 258.6 | 10.3 | 230.1 | 287.0 | ||
| Control | 243.7 | 11.0 | 213.3 | 274.2 | ||
| Ventrolateral periaqueductal gray (VLPAG) | −4.72 mm | Acquisition, 3 | 359.3 | 13.4 | 322.2 | 396.5 |
| Extinction | 326.5 | 13.5 | 289.2 | 363.7 | ||
| Control | 315.1 | 14.4 | 275.3 | 355.0 | ||
| Pontine reticular formation | −4.72 mm | Acquisition | 330.9 | 11.1 | 300.2 | 361.6 |
| Extinction | 308.4 | 11.1 | 277.6 | 339.1 | ||
| Control | 313.9 | 11.9 | 281.0 | 346.8 | ||
Regional FDG uptake values are expressed as nanocuries of isotope incorporation per gram tissue wet weight. Indicated group differences are significant at p < 0.01 after ANCOVA and at p < 0.05 after correction by the Hochberg procedure for multiple group comparisons. 1, Extinction group significantly greater than both acquisition and control. 2, Acquisition group significantly greater than extinction. 3, Acquisition group significantly greater than control.