Table 4. Unadjusted and adjusted risks for MACEs.
| Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Non-DM | Reference | Reference | ||
| New-DM | 0.87 (0.70–1.09) | 0.235 | 0.94 (0.72–1.23) | 0.648 |
| Known-DM | 1.60 (1.45–1.76) | <0.001 | 1.20 (1.06–1.35) | 0.004 |
| Old age (>60 years) | 2.16 (1.93–2.41) | <0.001 | 1.38 (1.19–1.60) | <0.001 |
| Male sex | 0.67 (0.60–0.73) | <0.001 | 0.80 (0.70–0.92) | 0.001 |
| BMI group (>24 kg/m2) | 0.71 (0.65–0.79) | <0.001 | 0.86 (0.76–0.96) | 0.010 |
| STEMI | 0.96 (0.88–1.06) | 0.445 | 0.96 (0.86–1.09) | 0.536 |
| Current smoking | 0.65 (0.58–0.72) | <0.001 | 0.97 (0.85–1.12) | 0.715 |
| LVEF (<50%) | 1.92 (1.74–2.13) | <0.001 | 1.48 (1.31–1.66) | <0.001 |
| Killips class (III, IV) | 3.15 (2.84–3.50) | <0.001 | 1.55 (1.34–1.80) | <0.001 |
| Multivessel disease | 1.83 (1.66–2.03) | <0.001 | 1.54 (1.38–1.74) | <0.001 |
| Post-TIMI flow (TIMI ≤2) | 2.17 (1.75–2.68) | <0.001 | 1.52 (1.16–1.99) | 0.003 |
| Hypertension | 1.61 (1.45–1.79) | <0.001 | 1.32 (1.15–1.50) | <0.001 |
| Dyslipidemia | 0.76 (0.65–0.89) | 0.001 | 0.85 (0.70–1.02) | 0.078 |
| Previous myocardial infarction | 1.60 (1.38–1.86) | <0.001 | 1.41 (1.17–1.70) | <0.001 |
| Renal failure (Cr >2.0 mg/dL) | 3.39 (2.96–3.88) | <0.001 | 2.13 (1.77–2.57) | <0.001 |
BMI = body mass index; CI = confidence interval; Cr = creatinine; DM = diabetes mellitus; HR = hazard ratio; known-DM = previously diagnosed diabetes mellitus; LVEF = left ventricular ejection fraction; MACE = major adverse cardiac event; new-DM = newly diagnosed diabetes mellitus; STEMI = ST-segment elevation myocardial infarction; TIMI = thrombolysis in myocardial infarction.