Table 4. Literature review of MAT in children (15 studies, available in full text).
| Authors | Year | Number | Sex (M:F) | Age | Comorbidity | Outcomes | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Median age | Infant | Structural heart disease | Pulmonary disease | RASopathy syndrome | Control rate (%) | Mortality | ||||
| Farooki and Green9) | 1977 | 2 | 2:0 | 0.1 months | 2/2 | 0/2 | 0/2 | 0/2 | 100 | 0/2 |
| Bisset et al.12) | 1981 | 10 | 8:2 | 1 months (1 day–18 years) | 5/10 | 5/10 | 1/10 | 1/10 | 90 | 1/10 |
| Liberthson and Colan5) | 1982 | 9 | 4:5 | 0.4 months (1 day–5 months) | 9/9 | 0/9 | 2/9 | 1/9 | 89 | 0/9 |
| Yeager et al.6) | 1984 | 4 | 3:1 | 1.1 months (1 day–10 months) | 4/4 | 2/4 | 0/4 | 1/4 | 50 | 3/4 |
| Zeevi et al.22) | 1986 | 1 | 1:0 | 3 years | 0/1 | 1/1 | 0/1 | 0/1 | 100 | 0/1 |
| Houyel et al.23) | 1990 | 2 | 1:1 | 1.3 months | 2/2 | 0/2 | 0/2 | 0/2 | 100 | 0/2 |
| Dodo et al.7) | 1995 | 9 | 5:4 | 0.5 months (1 day–30 months) | 7/9 | 7/9 | 2/9 | 3/9 | 44 | 2/9 |
| Salim et al.8) | 1995 | 5 | 3:2 | 1.3 months (1 day–8 months) | 5/5 | 3/5 | 2/5 | n/a | 80 | 1/5 |
| Fish et al.4) | 1996 | 7 | 5:2 | 2 months (1 day–11 months) | 7/7 | 1/7 | 3/7 | 0/7 | 100 | 0/7 |
| Cetta et al.24) | 1997 | 1 | 1:0 | 9 months | 1/1 | 0/1 | 0/1 | 0/1 | 100 | 0/1 |
| Bradley et al.1) | 2001 | 21 | 14:7 | 1.8 months (1 day–7.3 years) | 20/21 | 7/21 | 6/21 | 2/21 | 94 | 1/17 |
| Hsieh et al.15) | 2006 | 2 | 1:1 | 1 day, 5 years | 1/2 | 1/2 | 2/2 | 0/2 | 100 | 0/2 |
| Bouziri et al.25) | 2011 | 1 | 1:0 | 12 days | 1/1 | 1/1 | 0/1 | 0/1 | 100 | 0/1 |
| Pregowska et al.26) | 2014 | 1 | 1:0 | 2 months | 1/1 | 1/1 | 0/1 | 1/1 | 100 | 0/1 |
| Tutar et al.14) | 2016 | 1 | 0:1 | 13 years | 0/1 | 1/1 | 0/1 | 0/1 | 100 | 0/1 |
| This report | 2017 | 33 | 19:14 | 1.7 months (1 day–14.2 years) | 27/33 | 14/33 | 8/33 | 6/33 | 84 | 4/31 |