Fig. 5.
GSK specifically inhibited the PERK branch of the UPR. (A) GSK suppressed the elevation of the PERK branch protein levels induced by TM treatment, while showed no effect on the IRE1 and ATF6α branches. (B) Representative Western blot bands of the activated UPR effectors were present with or without TM, GSK, and 4μ8C treatment. *P<0.05 vs. the untreated control group; #P<0.05 vs. the TM group.