Table 1.
Baseline serum parameters of WT and Trpv4 KO control mice. n = 6 n = 4 for WT and n = 5 for Trpv4 KO mice, two-tailed unpaired t-test. n.a. = not applicable.
| Serum parameter | Unit | WT | Trpv4 KO | P-value | ||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| Sodium | mmol/L | 145,86 | 1,07 | 148,00 | 1,41 | 0,019 |
| Potassium | mmol/L | 4,71 | 0,42 | 5,05 | 0,82 | 0,382 |
| Chloride | mmol/L | 113,00 | 2,58 | 115,50 | 1,29 | 0,108 |
| Ionized Calcium | mmol/L | 1,28 | 0,05 | 1,28 | 0,04 | 1,000 |
| Total Carbon Dioxide | mmol/L | 21,57 | 0,98 | 18,00 | 2,45 | 0,007 |
| Glucose | mg/dL | 203,71 | 19,31 | 236,50 | 18,45 | 0,023 |
| Urea Nitrogen | mg/dL | 7,49 | 1,89 | 9,25 | 0,54 | 0,108 |
| Creatinine | umol/L | <18 | n.a. | <18 | n.a. | n.a. |
| Hematocrit | % PCV | 38,71 | 2,06 | 41,50 | 0,58 | 0,029 |
| Hemoglobin | g/dL | 13,15 | 0,73 | 14,10 | 0,23 | 0,035 |
| Anion Gap | mmol/L | 16,71 | 1,98 | 20,25 | 1,26 | 0,011 |