Fig. 4.

EIF4A3 binds upstream of exon–exon junctions. a Number of JAMM peaks located on genomic target classes for human EIF4A3 and MAGOH. Priority of target classes as in Fig. 3. b Histogram of crosslinked nucleotide positions for human EIF4A3, MAGOH and the corresponding control. EIF4A3 and MAGOH show increased binding 20–30 nucleotides upstream of exon–exon junctions, binding decreased with increasing distance to exon–exon junctions whereas the control is uniformly distributed. c Number of JAMM peaks located on genomic target classes for Drosophila EIF4A3 and MAGOH. Priority of target classes as in Fig. 3. d Histogram of crosslinked nucleotide positions for Drosophila EIF4A3, MAGOH and the corresponding control. EIF4A3 shows increased binding 20–30 nucleotides upstream of exon–exon junctions whereas crosslinked nucleotides of MAGOH and the control are not specifically enriched