Table 1.
Demographics and clinical data of the two study groups
| Characteristic | SSTS | cFNB | p value |
|---|---|---|---|
| (95) | (87) | ||
| Patient age (years) | 66.2 ± 7.6 | 68.7 ± 6.6 | < 0.05a |
| Female/Male | 66/29 | 46/41 | < 0.001 |
| BMI (mean ± SD) | 29.3 ± 5.0 | 29.8 ± 5.4 | nsa |
| Comorbidities, n (%) | |||
| Hypertension | 63 (66.3) | 36 (41.4) | < 0.001a |
| Diabetes | 12 (12.6) | 14 (16.1) | nsb |
| Heart diseases | 13 (13.7) | 12 (13.8) | nsb |
| Other | 57 (60.0) | 6 (6.9) | < 0.001b |
| Pain, mean ± SD | |||
| NRS T1 | 1.96 ± 0.93 | 0.60 ± 1.06 | < 0.001b |
| NSR T2 | 1.79 ± 0.90 | 0.40 ± 0.58 | < 0.001b |
| NSR T3 | 1.21 ± 0.94 | 0.18 ± 0.42 | < 0.001b |
| NRS T4 | x | 0.16 ± 0.41 | |
| mNRS T1 | 1.85 ± 0.96 | 2.06 ± 1.9 | < 0.001b |
| mNRS T2 | 1.62 ± 1.15 | 1.94 ± 1.5 | < 0.01b |
| mNRS T3 | 1.16 ± 0.73 | 1.33 ± 0.93 | < 0.05b |
| mNRS T4 | x | 1.94 ± 1.08 | |
| Rescue analgesic, n (%) | |||
| T1 | 5 (5.3) | 22 (25.3) | < 0.001c |
| T2 | 0 (0.0) | 13 (14.9) | |
| T3 | 0 (0.0) | 9 (10.3) | |
| AEs, n (%) | |||
| Overall n. events | 7 | 132 | < 0.001c |
| Overall n. patients (%) Nausea | 1 (1) | 42 (48) | < 0.001c |
| Vomiting | 2 (1) | 24 (28) | < 0.001c |
| PONV | 2 (2) | 61 (70) | < 0.0013 |
| Erythema | 1 (1) | 5 (6) | ns |
| Dizziness | 1 (1) | 15 (17) | < 0.001c |
| Numbness | 0 | 47 (54) | |
| LOS, n patients (%) | |||
| = 4 days | 95 (100.0%) | 32 (36.8%) | |
| 5–7 days | 0 (0.0%) | 55 (63.2%) | |
Abbreviations: AEs adverse events, BMI body mass index, LOS length of hospital stay, NRS numeric rating score pain at rest, mNRS movement-evoked NRS. T1-T4, postoperative days 1–4
Statistical analyses used: aT-Test; b Kruskal-Wallis; c Chi-squared test