Table 1. Summary of datasets included for meta-analysis.
Study ID | Author | Year | Ethnicity | Genotyping method | Study design | Case/control | SNP loci | GD patient | Healthy control | pHWE | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GG | GA | AA | GG | GA | AA | |||||||||
1 | Duraes et al. [9] | 2014 | European | Taqman | CC | 111/735 | rs1800629 | 72 | 34 | 5 | 562 | 156 | 17 | 0.122 |
2 | Kutluturk et al. [11] | 2013 | Asian | PCR-SSP | CC | 100/124 | rs1800629 | 73 | 24 | 3 | 103 | 15 | 6 | 0.000 |
3 | Jurecka-Lubieniecka et al. [17] | 2013 | European | PCR-RFLP | CC | 555/341 | rs1800629 | 299 | 231 | 25 | 259 | 71 | 11 | 0.032 |
4 | Anvari et al. [12] | 2010 | Asian | PCR-SSP | CC | 105/137 | rs1800629 | 56 | 44 | 5 | 98 | 39 | 0 | 0.052 |
rs361525 | 74 | 33 | 0 | 79 | 57 | 1 | 0.007 | |||||||
5 | Gu et al. [13] | 2010 | Asian | MassArray™ | CC | 426/315 | rs1800629 | 368 | 56 | 2 | 263 | 51 | 1 | 0.369 |
rs361525 | 408 | 20 | 0 | 281 | 34 | 0 | 0.311 | |||||||
6 | Shiau et al. [14] | 2007 | Asian | PCR-RFLP | CC | 187/101 | rs1800629 | 168 | 16 | 3 | 77 | 24 | 0 | 0.175 |
rs361525 | 50 | 70 | 3 | 186 | 3 | 0 | 0.912 | |||||||
7 | Chen et al. [15] | 2005 | Asian | PCR-RFLP | CC | 95/60 | rs1800629 | 85 | 10 | 0 | 49 | 9 | 2 | 0.083 |
8 | Bednarczuk et al. [8] | 2004 | European | PCR-SSP | CC | 228/248 | rs1800629 | 122 | 96 | 10 | 172 | 72 | 4 | 0.25 |
rs361525 | 220 | 8 | 0 | 225 | 22 | 1 | 0.563 | |||||||
9 | Simmonds et al. [6] | 2004 | European | PCR-RFLP | CC | 810/836 | rs361525 | 660 | 145 | 5 | 727 | 105 | 4 | 0.92 |
10 | Kamizono et al. [16] | 2000 | Asian | PCR-SSOP | CC | 173/575 | rs1800629 | 169 | 4 | 0 | 556 | 18 | 1 | 0.04 |
rs361525 | 166 | 7 | 0 | 552 | 23 | 0 | 0.62 |
Abbreviations: CC, case/control; PCR-SSOP, PCR-sequence specific oligonucleotide polymorphism; PCR-RFLP, PCR-restriction fragment length polymorphism; PCR-SSP, PCR-sequence specific primer.