Table 5.

Logistic regression models exploring associations between different outcomes and age at diagnosis and healthy lifestyle (never smoked and sports activities ≥2 h/week) in patients with DSD.

	Age at diagnosis		Healthy lifestyle
	OR (95% CI)	P value	OR (95% CI)	P value
Longstanding health problem?*	1.04 (1.02–1.05)	<0.0001	0.47 (0.20–1.09)	0.0853
Health issues limited daily life, past 6 m	1.04 (1.03–1.06)	<0.0001	0.68 (0.29–1.61)	0.3702
Obesity	1.01 (1.00–1.03)	0.06782	0.32 (0.12–0.87)	0.0199
Type 2 diabetes	1.05 (1.03–1.08)	0.0002	0.20 (0.05–0.81)	0.0214
Hypertension	1.03 (1.02–1.04)	0.0003	0.71 (0.22–2.81)	0.8245
Dyslipidaemia	1.05 (1.02–1.07)	<0.0001	0.62 (0.41–0.92)	0.0192
CV disease	1.03 (1.01–1.03)	<0.0001	0.87 (0.58–1.27)	0.4728
Psychiatric disorders	1.02 (1.00–1.03)	0.0119	0.29 (0.12–0.66)	0.0033
Osteoporosis	1.06 (1.04–1.08)	<0.0001	1.64 (0.39–11.39)	0.5460
Fractures	1.04 (1.02–1.05)	<0.0001	0.80 (0.30–2.40)	0.6710
Autoimmune disorders	1.02 (1.01–1.03)	0.0064	1.08 (0.47–2.64)	0.9763
Joint problems	1.03 (1.01–1.05)	0.0046	0.85 (0.23–4.20)	0.7008
Visual issues	1.01 (1.00–1.03)	0.0565	5.69 (1.62–36.11)	0.0207
Hearing issues	1.01 (0.99–1.02)	0.2777	0.39 (0.16–1.00)	0.0469
Neurological disorders	1.02 (1.00–1.04)	0.0287	0.51 (0.16–2.00)	0.1153
Urinary issues	0.96 (0.94–0.98)	0.0006	0.55 (0.18–2.08)	0.3289
Any disorder*	1.04 (1.02–1.06)	0.0002	0.31 (0.07–0.93)	0.0003

The higher OR the higher risk per each year later the DSD diagnosis was made. Healthy lifestyle was compared to those with not having a healthy lifestyle. Bold indicates P < 0.05. No associations were found with waist/hip ratio, suicide attempts, renal and gastrointestinal disorders or malignancy (except females with age at diagnosis 1.04 (1.01–1.08), P = 0.0057) (not shown).

*Except the DSD.

CV, cardiovascular; OR, odds ratio.