Table 4.

Comparison of the non-laboratory and fasting cholesterol INTERHEART risk scores for predicting cardiovascular disease

	N	Outcome* (%)	Discrimination, C-statistic (95% CI)		p Value
			NL-IHRS	FC-IHRS
Overall	85 078	1965 (2.31)	0.73 (0.72 to 0.74)	0.74 (0.73 to 0.75)	<0.001
Geographic region
South Asia	7552	365 (4.83)	0.68 (0.65 to 0.71)	0.69 (0.66 to 0.72)	0.15
China	35 882	549 (1.53)	0.69 (0.67 to 0.71)	0.69 (0.67 to 0.72)	0.81
Southeast Asia	3542	87 (2.46)	0.73 (0.68 to 0.77)	0.72 (0.68 to 0.77)	0.65
Africa	789	39 (4.94)	0.65 (0.57 to 0.74)	0.68 (0.59 to 0.76)	0.49
North America/Europe	15 450	500 (3.24)	0.69 (0.67 to 0.71)	0.72 (0.70 to 0.74)	<0.001
Middle East	4763	110 (2.31)	0.77 (0.72 to 0.81)	0.78 (0.73 to 0.82)	0.56
South America	17 100	315 (1.84)	0.72 (0.69 to 0.75)	0.73 (0.71 to 0.76)	0.26
Country income status
HIC	11 287	304 (2.69)	0.68 (0.65 to 0.71)	0.71 (0.68 to 0.73)	0.015
MIC	65 720	1266 (1.93)	0.73 (0.71 to 0.74)	0.73 (0.72 to 0.75)	0.12
LIC	8071	395 (4.89)	0.67 (0.65 to 0.70)	0.69 (0.66 to 0.72)	0.07

*Cardiovascular disease defined as cardiac death, stroke, myocardial infarction, heart failure and revascularisation.

FC-IHRS, fasting cholesterol INTERHEART risk score; HIC, high-income countries; LIC, low-income country; MIC, middle-income country; NL-IHRS, non-laboratory INTERHEART risk score; PURE, Prospective Urban Rural Epidemiology.