Table 4.
N | Outcome* (%) | Discrimination, C-statistic (95% CI) | p Value | ||
NL-IHRS | FC-IHRS | ||||
Overall | 85 078 | 1965 (2.31) | 0.73 (0.72 to 0.74) | 0.74 (0.73 to 0.75) | <0.001 |
Geographic region | |||||
South Asia | 7552 | 365 (4.83) | 0.68 (0.65 to 0.71) | 0.69 (0.66 to 0.72) | 0.15 |
China | 35 882 | 549 (1.53) | 0.69 (0.67 to 0.71) | 0.69 (0.67 to 0.72) | 0.81 |
Southeast Asia | 3542 | 87 (2.46) | 0.73 (0.68 to 0.77) | 0.72 (0.68 to 0.77) | 0.65 |
Africa | 789 | 39 (4.94) | 0.65 (0.57 to 0.74) | 0.68 (0.59 to 0.76) | 0.49 |
North America/Europe | 15 450 | 500 (3.24) | 0.69 (0.67 to 0.71) | 0.72 (0.70 to 0.74) | <0.001 |
Middle East | 4763 | 110 (2.31) | 0.77 (0.72 to 0.81) | 0.78 (0.73 to 0.82) | 0.56 |
South America | 17 100 | 315 (1.84) | 0.72 (0.69 to 0.75) | 0.73 (0.71 to 0.76) | 0.26 |
Country income status | |||||
HIC | 11 287 | 304 (2.69) | 0.68 (0.65 to 0.71) | 0.71 (0.68 to 0.73) | 0.015 |
MIC | 65 720 | 1266 (1.93) | 0.73 (0.71 to 0.74) | 0.73 (0.72 to 0.75) | 0.12 |
LIC | 8071 | 395 (4.89) | 0.67 (0.65 to 0.70) | 0.69 (0.66 to 0.72) | 0.07 |
*Cardiovascular disease defined as cardiac death, stroke, myocardial infarction, heart failure and revascularisation.
FC-IHRS, fasting cholesterol INTERHEART risk score; HIC, high-income countries; LIC, low-income country; MIC, middle-income country; NL-IHRS, non-laboratory INTERHEART risk score; PURE, Prospective Urban Rural Epidemiology.