Table 2.
Demographics and Comorbidities for 318 Patients With MSSA Bacteremia According to Penicillin Allergy
| Characteristics | Allergy History | P | |
|---|---|---|---|
| Nonallergic (n = 252), No. (%) |
Penicillin-Allergic (n = 66), No. (%) |
||
| Demographics | |||
| Age, mean (SD), y | 56.6 (15) | 60.9 (18) | .05 |
| Male | 169 (67) | 34 (51) | .02 |
| Comorbidities | |||
| Myocardial infarction | 56 (22) | 24 (36) | .03 |
| Heart failure | 101 (40) | 38 (58) | .01 |
| Vascular disease | 51 (20) | 27 (41) | <.01 |
| Cerebrovascular disease | 80 (32) | 34 (52) | <.01 |
| Dementia | 9 (3) | 2 (3) | .99 |
| Pulmonary | 90 (36) | 27 (41) | .47 |
| Connective tissue disease | 30 (12) | 9 (14) | .68 |
| Peptic ulcer disease | 27 (11) | 10 (15) | .38 |
| Liver disease | 25 (10) | 5 (8) | .64 |
| Diabetes | 128 (51) | 40 (60) | .17 |
| Diabetes with complications | 71 (28) | 24 (36) | .22 |
| Paraplegia | 15 (6) | 2 (3) | .54 |
| Renal disease | 133 (53) | 46 (69) | .02 |
| Cancer | 77 (31) | 12 (18) | .05 |
| Metastatic cancer | 39 (16) | 4 (6) | .07 |
| Severe liver disease | 24 (10) | 2 (3) | .13 |
| HIV | 7 (3) | 1 (2) | .99 |
| Charlson comorbidity index, mean (SD) | 5.6 (3) | 6.2 (3) | .23 |
| SOFA score, mean (SD) | 3.1 (3) | 3.3 (3) | .58 |
Abbreviation: MSSA, methicillin-susceptible Staphylococcus aureus.