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Exonuclease activities of APE2 with purified proteins in vitro. (A) In vitro analysis of exonuclease activity of GST-APE2 with the presence or absence of WT or mutant His-tagged PCNA using the FAM-labeled gapped dsDNA structure. (B) In vitro analysis of exonuclease activity of WT and mutant GST-APE2 with the presence or absence of WT His-tagged PCNA using the FAM-labeled gapped dsDNA structure.
