. 2017 Aug 23;31(1):97–107. doi: 10.1093/ajh/hpx138

Table 2.

Primary and secondary outcomes stratified by treatment group and race/ethnicity

Outcome	Race/ethnicity	Intensive arm			Standard arm			Intensive vs. standard hazard ratio			Interaction P value
Outcome	Race/ethnicity	N	Events	% per Year	N	Events	% per Year	HR	Lower 95% CI	Upper 95% CI	Interaction P value
Primary outcome^a	(Non-Hispanic) White	2,698	167	1.9	2,701	229	2.7	0.70	0.57	0.86	0.85
	(Non-Hispanic) Black	1,379	64	1.5	1,423	93	2.1	0.71	0.51	0.98
	Hispanic	503	20	1.2	481	26	1.7	0.62	0.33	1.15
Myocardial infarction	(Non-Hispanic) White	2,698	69	0.8	2,701	88	1.0	0.77	0.56	1.05	0.63
	(Non-Hispanic) Black	1,379	22	0.5	1,423	35	0.8	0.64	0.36	1.09
	Hispanic	503	9	0.6	481	13	0.8	0.48	0.18	1.18
Acute coronary syndrome	(Non-Hispanic) White	2,698	30	0.3	2,701	26	0.3	1.15	0.68	1.95	0.35
	(Non-Hispanic) Black	1,379	7	0.2	1,423	9	0.2	0.86	0.30	2.33
	Hispanic	503	3	0.2	481	5	0.3	0.57	0.11	2.34
Stroke	(Non-Hispanic) White	2,698	44	0.5	2,701	49	0.6	0.87	0.58	1.32	0.38
	(Non-Hispanic) Black	1,379	14	0.3	1,423	22	0.5	0.66	0.33	1.28
	Hispanic	503	6	0.4	481	5	0.3	1.05	0.31	3.69
Heart failure	(Non-Hispanic) White	2,698	40	0.5	2,701	70	0.8	0.55	0.37	0.81	0.27
	(Non-Hispanic) Black	1,379	22	0.5	1,423	29	0.6	0.80	0.45	1.40
	Hispanic	503	4	0.2	481	5	0.3	0.61	0.15	2.35
Cardiovascular death	(Non-Hispanic) White	2,698	23	0.3	2,701	45	0.5	0.49	0.29	0.81	0.098
	(Non-Hispanic) Black	1,379	13	0.3	1,423	18	0.4	0.77	0.37	1.57
	Hispanic	503	1	0.1	481	6	0.4	0.17	0.01	1.08
Non-CVD death	(Non-Hispanic) White	2,698	57	0.6	2,701	82	0.9	0.69	0.49	0.97	0.006
	(Non-Hispanic) Black	1,379	30	0.7	1,423	26	0.6	1.16	0.68	1.98
	Hispanic	503	12	0.7	481	4	0.3	3.28	0.98	14.77
All-cause mortality	(Non-Hispanic) White	2,698	89	1.0	2,701	144	1.6	0.61	0.47	0.80	0.008
	(Non-Hispanic) Black	1,379	51	1.2	1,423	56	1.2	0.92	0.63	1.35
	Hispanic	503	19	1.1	481	12	0.8	1.58	0.73	3.62
Primary outcome or death	(Non-Hispanic) White	2,698	222	2.6	2,701	310	3.6	0.70	0.59	0.83	0.082
	(Non-Hispanic) Black	1,379	94	2.2	1,423	122	2.7	0.78	0.59	1.030
	Hispanic	503	35	2.1	481	31	2.0	1.00	0.60	1.67

Abbreviations: CI, confidence interval, CVD, cardiovascular disease primary outcome; HR, hazard ratio.

^aThe primary outcome includes the first occurrence of myocardial infarction, acute coronary syndrome, stroke, heart failure, or death from cardiovascular causes. Median follow-up of 3.26 years.