Table 2.
Systolic salt sensitivity of blood pressure (SSBP) by univariate and multivariate analysis for tagging SNP rs2540923
| Cohort | Sample size | Univariate analysis | Multivariate analysisa | ||
|---|---|---|---|---|---|
| β (95% CI) | P value | β (95% CI) | P value | ||
| New | 270 | 6.75 (2.70, 10.81) | 0.001 | 4.84 (0.84, 8.83) | 0.01 |
| Combined | 615 | 5.25 (1.67, 8.84) | 0.004 | 5.35 (1.86, 8.83) | 0.003 |
Abbreviations: BMI, body mass index; CI, confidence interval; SNP, single-nucleotide polymorphism.
aAdjustment made for age, sex, race, BMI, disease state (hypertensive vs. normal and diabetic vs. hypertensive and normal). The SNP rs2540923 was stratified by comparing the GG group to the AG + AA group.