Table 3.

Associations between measures of stiffness and inflammatory markers over time (longitudinal)

	PWV P value (β)	CPP P value (β)	AI P value (β)	PPA P value (β)
Fibrinogen	0.125 (0.039)	0.225 (−0.194)	0.697 (0.045)	0.952 (0.000)
Albumin	0.002 (0.202)	0.233 (0.490)	0.180 (0.402)	0.131 (−0.009)
IL-6	0.428 (0.035)	0.739 (−0.094)	0.379 (−0.181)	0.356 (−0.004)
IL-10	0.431 (0.032)	0.399 (−0.224)	0.021 (0.450)	0.521 (−0.002)
IL-1RA	0.255 (−0.034)	0.414 (−0.153)	0.092 (−0.231)	0.865 (−0.000)
IL-1 β	0.921 (0.005)	0.899 (0.037)	0.230 (−0.258)	0.411 (0.004)
TGF-β	0.479 (0.028)	0.684 (0.102)	0.724 (−0.065)	0.683 (−0.001)
TNF-α	0.391 (0.050)	0.162 (−0.518)	0.066 (−0.497)	0.069 (0.010)
hs-CRP	0.837 (0.006)	0.903 (0.024)	0.788 (−0.038)	0.753 (−0.001)
Inflam Score	0.346 (0.024)	0.340 (−0.151)	0.157 (−0.165)	0.975 (0.000)

Adjusted model controls for mean arterial pressure, age, race, sex, diabetes, active smoking, hemoglobin, estimated glomerular filtration rate, and angiotensin converting enzyme inhibitor/angiotensin receptor blocker use. Abbreviations: AI, augmentation index; CPP, central pulse pressure; hs-CRP, high-sensitivity C-reactive protein; Inflam Score = inflammation score; IL, interleukin; PPA, pulse pressure amplification; PWV, pulse wave velocity; TGF, transforming growth factor; TNF, tumor necrosis factor; Uprot, 24-hour urine protein.